Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8658344 | 0.91 | GLA (0.33) | KCNH2SMN1; SMN2HRH3 | |
| SCHEMBL8658295 | 0.90 | ALDH1A1 (0.33) | S1PR1RECQLSMN1; SMN2 | |
| SCHEMBL8655443 | 0.89 | ITGB3 (0.32) | RECQLSMN1; SMN2 | |
| SCHEMBL8656293 | 0.88 | OPRL1 (0.35) | — | |
| SCHEMBL8659427 | 0.87 | HTR7 (0.41) | — | |
| SCHEMBL8657712 | 0.86 | SMN1; SMN2 (0.42) | SMN1; SMN2 | |
| SCHEMBL8656871 | 0.85 | ITGB3 (0.32) | RECQLSMN1; SMN2 | |
| SCHEMBL8659458 | 0.84 | FPR3 (0.32) | SMN1; SMN2 | |
| SCHEMBL8657864 | 0.82 | SMN1; SMN2 (0.43) | SMN1; SMN2 | |
| SCHEMBL8659558 | 0.82 | HTR7 (0.38) | RECQLSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776937-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-07-07 | — | — | US | disclosed |