Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
| ▸ | FABP3 | P05413 | 1/20 | 0.31 |
| ▸ | FABP4 | P15090 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11449784 | 0.82 | GABRA1 (0.42) | ALOX15CYP2D6CYP1A2GABRA1GABRB2 | |
| SCHEMBL4482820 | 0.77 | CA1 (0.46) | ALOX15ALOX12CYP1A2GABRA1GABRB2 | |
| SCHEMBL8204666 | 0.71 | ALOX15 (0.49) | ALOX15ALOX12HSPA5CYP2D6CYP1A2 | |
| SCHEMBL28226021 | 0.71 | HSP90AB1 (0.35) | ALOX15ALOX12GABRA1GABRB2CA1 | |
| SCHEMBL19658048 | 0.69 | TYR (0.43) | ALOX15ALOX12CYP1A2GABRA1GABRB2 | |
| SCHEMBL5381348 | 0.69 | LMNA (0.41) | ALOX15ALOX12CYP1A2GABRA1GABRB2 | |
| SCHEMBL28404083 | 0.69 | HSPA5 (0.56) | ALOX15HSPA5CYP2D6CYP1A2GABRA1 | |
| SCHEMBL9721890 | 0.67 | CA2 (0.48) | ALOX15CYP2D6CYP1A2GABRA1GABRB2 | |
| SCHEMBL28714084 | 0.67 | TSHR (0.42) | ALOX15ALOX12GAAHSP90AA1HSP90AB1 | |
| SCHEMBL28716048 | 0.67 | PTPN1 (0.43) | GABRA1CA1CA2PTPN1PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5723694-A | REACTION OF FORMALDEHYDE WITH PHENOL AND CATALYTIC HYDROGENATION | BAYER AKTIENGESELLSCHAFT (DE) | 1998-03-03 | — | — | US | disclosed |