Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 8/20 | 0.60 |
| ▸ | ESR1 | P03372 | 7/20 | 0.60 |
| ▸ | MAOA | P21397 | 1/20 | 0.60 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.60 |
| ▸ | MAOB | P27338 | 1/20 | 0.60 |
| ▸ | TTR | P02766 | 2/20 | 0.46 |
| ▸ | BCL2 | P10415 | 3/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | PTPRC | P08575 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL136078 | 0.82 | CDC25B (0.55) | MAOAMAOBBCL2MCL1ALDH1A1 | |
| SCHEMBL5506572 | 0.82 | CDC25B (0.55) | MAOAMAOBBCL2MCL1ALDH1A1 | |
| SCHEMBL8657198 | 0.80 | S100A4 (0.58) | MAOBTTRBCL2MCL1ALDH1A1 | |
| 2-Hydroxyanthraquinone SCHEMBL28843858 | 0.80 | ESR1 (0.86) | ESR2ESR1MAOAUGT1A1MAOB | |
| 2-Hydroxyanthraquinone SCHEMBL498619 | 0.80 | ESR1 (0.86) | ESR2ESR1MAOAUGT1A1MAOB | |
| SCHEMBL3673942 | 0.80 | CDC25B (0.41) | MAOAMAOBMCL1ALDH1A1RAB9A | |
| SCHEMBL143100 | 0.78 | ESR1 (0.82) | ESR2ESR1MAOAUGT1A1MAOB | |
| 2-Hydroxyanthraquinone SCHEMBL28853822 | 0.78 | ESR1 (0.82) | ESR2ESR1MAOAUGT1A1MAOB | |
| SCHEMBL30366712 | 0.78 | ESR1 (0.82) | ESR2ESR1MAOAUGT1A1MAOB | |
| SCHEMBL28320135 | 0.78 | ESR1 (0.82) | ESR2ESR1MAOAUGT1A1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5807837-A | ADMINISTERING TO TREAT HIV INFECTIONS TO INHIBIT THE REPLICATION OF FOREIGN NUCLEIC ACIDS IN A NORMAL CELL | SANKYO COMPANY, LIMITED (JP) | 1998-09-15 | — | — | US | disclosed |
| US-5674856-A | TREATMENT AND PROPHYLAXIS OF VIRAL INFECTIONS, INCLUDING AIDS AND TUMORS | SANKYO COMPANY, LIMITED (JP) | 1997-10-07 | — | — | US | disclosed |
| EP-0611075-B1 | Modified oligodeoxyribonucleotides, their preparation and their therapeutic use | SANKYO CO (JP) | 1996-12-18 | — | — | EP | disclosed |
| EP-0611075-A1 | Modified oligodeoxyribonucleotides, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1994-08-17 | — | — | EP | disclosed |