SCHEMBL5506572

SCHEMBL5506572

O=C1c2[c]cccc2C(=O)c2ccccc21.O=C1c2[c]cccc2C(=O)c2ccccc21

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDC25B P30305 4/20 0.55
MEN1 O00255 3/20 0.55
KMT2A Q03164 3/20 0.55
MAOA P21397 5/20 0.46
MAPK1 P28482 4/20 0.46
MAPT P10636 4/20 0.46
SMN1; SMN2 Q16637 4/20 0.46
KDM4E B2RXH2 3/20 0.46
LMNA P02545 3/20 0.46
RAB9A P51151 3/20 0.46
BLM P54132 3/20 0.46
APAF1 O14727 2/20 0.46
TDP2 O95551 2/20 0.46
NPC1 O15118 2/20 0.46
PLIN1 O60240 2/20 0.46
PTPRC P08575 2/20 0.46
PLIN5 Q00G26 2/20 0.46
ABHD5 Q8WTS1 2/20 0.46
POLB P06746 2/20 0.46
S100A4 P26447 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL136078 1.00 CDC25B (0.55) CDC25BMEN1KMT2AMAOAMAPK1
SCHEMBL3673942 0.93 CDC25B (0.41) CDC25BMEN1KMT2AMAOAMAPK1
SCHEMBL2077973 0.91 MEN1 (0.55) CDC25BMEN1KMT2AMAOAMAPK1
SCHEMBL18844 0.91 S100A4 (0.52) CDC25BMEN1KMT2AMAOAMAPK1
SCHEMBL9366483 0.91 MEN1 (0.46) CDC25BMEN1KMT2AMAOAMAPK1
SCHEMBL56824 0.83 CDC25B (0.55) CDC25BMEN1KMT2AMAOAMAPK1
SCHEMBL8657198 0.82 S100A4 (0.58) CDC25BMEN1KMT2AMAPK1MAPT
SCHEMBL8658476 0.82 ESR2 (0.60) MAOAMAPK1MAPTSMN1; SMN2RAB9A
SCHEMBL6003309 0.74 MEN1 (0.50) CDC25BMEN1KMT2AMAOAMAPK1
Anthraquinone SCHEMBL14943 0.74 MEN1 (1.00) CDC25BMEN1KMT2AMAOAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1299479-B2 PIGMENTARY COPPER PHTHALOCYANINE SOLID SOLUTION AND TRANSPARENT DISPERSION COMPRISING IT CIBA SC HOLDING AG (CH) 2007-02-21 EP disclosed