SCHEMBL136078

SCHEMBL136078

O=C1c2[c]cccc2C(=O)c2ccccc21

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDC25B P30305 4/20 0.55
MEN1 O00255 3/20 0.55
KMT2A Q03164 3/20 0.55
MAOA P21397 5/20 0.46
MAPK1 P28482 4/20 0.46
MAPT P10636 4/20 0.46
SMN1; SMN2 Q16637 4/20 0.46
KDM4E B2RXH2 3/20 0.46
LMNA P02545 3/20 0.46
RAB9A P51151 3/20 0.46
BLM P54132 3/20 0.46
APAF1 O14727 2/20 0.46
TDP2 O95551 2/20 0.46
NPC1 O15118 2/20 0.46
PLIN1 O60240 2/20 0.46
PTPRC P08575 2/20 0.46
PLIN5 Q00G26 2/20 0.46
ABHD5 Q8WTS1 2/20 0.46
POLB P06746 2/20 0.46
S100A4 P26447 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5506572 1.00 CDC25B (0.55) CDC25BMEN1KMT2AMAOAMAPK1
SCHEMBL3673942 0.93 CDC25B (0.41) CDC25BMEN1KMT2AMAOAMAPK1
SCHEMBL2077973 0.91 MEN1 (0.55) CDC25BMEN1KMT2AMAOAMAPK1
SCHEMBL18844 0.91 S100A4 (0.52) CDC25BMEN1KMT2AMAOAMAPK1
SCHEMBL9366483 0.91 MEN1 (0.46) CDC25BMEN1KMT2AMAOAMAPK1
SCHEMBL56824 0.83 CDC25B (0.55) CDC25BMEN1KMT2AMAOAMAPK1
SCHEMBL8657198 0.82 S100A4 (0.58) CDC25BMEN1KMT2AMAPK1MAPT
SCHEMBL8658476 0.82 ESR2 (0.60) MAOAMAPK1MAPTSMN1; SMN2RAB9A
SCHEMBL6003309 0.74 MEN1 (0.50) CDC25BMEN1KMT2AMAOAMAPK1
Anthraquinone SCHEMBL14943 0.74 MEN1 (1.00) CDC25BMEN1KMT2AMAOAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3643 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3674290-B1 HETEROCYCLIC COMPOUND, COMPOSITION INCLUDING THE SAME, AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE HETEROCYCLIC COMPOUND SAMSUNG ELECTRONICS CO LTD (KR) 2024-05-22 EP claimed
US-11925106-B2 Condensed cyclic compound, composition including the same, and organic light-emitting device including the condensed cyclic compound SAMSUNG ELECTRONICS CO., LTD. (KR) 2024-03-05 US claimed
US-20240034885-A1 NEAR-INFRARED (NIR) TRANSPARENT NEUTRAL BLACK SOLID SOLUTION PIGMENT SUN CHEMICAL B.V. (NL) 2024-02-01 US claimed
US-20240026171-A1 Near-Infrared (NIR) transparent neutral black perylene solid solutions SUN CHEMICAL B.V. (NL) 2024-01-25 US claimed
US-20230415104-A1 CO2 PURIFICATION WITH ELECTROACTIVE POLYMERS TWELVE BENEFIT CORPORATION 2023-12-28 US claimed
WO-2023249805-A1 CO2 PURIFICATION SYSTEM AND METHOD USING CO2-ABSORBING ELECTRODE CELLS COMBINED WITH PURE CO2 REDUCTION IN AN ELECTROLYZER TO PRODUCE CARBON CONTAINING PRODUCTS TWELVE BENEFIT CORPORATION (US) 2023-12-28 WO claimed
EP-4263722-A1 NEAR-INFRARED (NIR) TRANSPARENT NEUTRAL BLACK SOLID SOLUTION PIGMENT Sun Chemical B.V. (NL) 2023-10-25 EP claimed
EP-4263723-A1 NEAR-INFRARED (NIR) TRANSPARENT NEUTRAL BLACK PERYLENE SOLID SOLUTIONS Sun Chemical B.V. (NL) 2023-10-25 EP claimed
CN-116761854-A Near Infrared (NIR) transparent neutral black solid solution pigment 太阳化学有限公司 2023-09-15 CN claimed
US-11706977-B2 Heterocyclic compound, composition including the same, and organic light-emitting device including the heterocyclic compound SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-07-18 US claimed
US-4116953-A 2-PHENYL-3,1-BENZOXAZIN-4-ONES, PIGMENTS BASF AKTIENGESELLSCHAFT (DE) 1978-09-26 US claimed
US-4052377-A PIGMENTS BASF AKTIENGESELLSCHAFT (DT) 1977-10-04 US claimed
US-4042591-A PIGMENTS, DISPERSE DYES SANDOZ LTD. (CH) 1977-08-16 US claimed
US-4042577-A POLYESTERS, POLYAMIDES, CELLULOSE ACETATES SANDOZ LTD. (CH) 1977-08-16 US claimed
US-4016149-A ABSORTION ONTO A COLOR REACTIVE DYE-SOLID PHASE SUPPORT RESEARCH CORPORATION (US) 1977-04-05 US claimed
US-4010162-A Substituted phenanthroline pigments ALLIED CHEMICAL CORPORATION (US) 1977-03-01 US claimed
US-3994854-A Pigmenting process employing acridone compounds and products produced thereby SANDOZ LTD. (CH) 1976-11-30 US claimed
US-3978062-A ORGANIC PIGMENTS SANDOZ LTD. (CH) 1976-08-31 US claimed
US-3972881-A VAT, CELLULOSE CIBA-GEIGY CORPORATION (US) 1976-08-03 US claimed
US-3953420-A Azo pigments derived from 2-hydroxy-3-carboxynaphthalene containing a substituted or unsubstituted phthalimide BADISCHE ANILIN- & SODA-FABRIK AKTIENGESELLSCHAFT (DT) 1976-04-27 US claimed