Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8659695 | 0.79 | DDB1 (0.40) | TSHRALDH1A1CYP1A2L3MBTL1KDM4E | |
| SCHEMBL8658338 | 0.75 | MMP1 (0.42) | TSHRALDH1A1CYP1A2PKMLMNA | |
| SCHEMBL7175387 | 0.72 | CYP1A2 (0.42) | TSHRALDH1A1CYP1A2KDM4ELMNA | |
| SCHEMBL8663561 | 0.71 | HSD17B10 (0.51) | TSHRALDH1A1PKMLMNAMAPT | |
| Hydrochloric Acid SCHEMBL7174330 | 0.71 | ALDH1A1 (0.42) | TSHRALDH1A1CYP1A2L3MBTL1KDM4E | |
| Hydrochloric Acid SCHEMBL7174333 | 0.71 | ALDH1A1 (0.42) | TSHRALDH1A1CYP1A2L3MBTL1KDM4E | |
| SCHEMBL7176699 | 0.68 | CTRB1 (0.67) | TSHRALDH1A1CYP1A2L3MBTL1CTRB1 | |
| SCHEMBL7176703 | 0.68 | CTRB1 (0.67) | TSHRALDH1A1CYP1A2L3MBTL1CTRB1 | |
| SCHEMBL8159980 | 0.68 | CTRB1 (0.67) | TSHRALDH1A1CYP1A2L3MBTL1CTRB1 | |
| SCHEMBL5169143 | 0.65 | ALDH1A1 (0.65) | TSHRALDH1A1CYP1A2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5767140-A | USEFUL FOR TREATING AIDS | SOUTHERN RESEARCH INSTITUTE (US) | 1998-06-16 | — | — | US | disclosed |