Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.52 |
| ▸ | HTT | P42858 | 4/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.51 |
| ▸ | PKM | P14618 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9067743 | 0.89 | CA12 (0.62) | LMNAHTTALDH1A1PKMSMN1; SMN2 | |
| SCHEMBL9272790 | 0.84 | LMNA (0.56) | LMNAHTTMAPK1ALDH1A1PKM | |
| SCHEMBL9766743 | 0.83 | ALDH1A1 (0.55) | LMNAALDH1A1PKMSMN1; SMN2MEN1 | |
| SCHEMBL9067555 | 0.82 | ALDH1A1 (0.61) | LMNAMAPK1ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL635208 | 0.80 | ALDH1A1 (0.70) | LMNAHTTMAPK1ALDH1A1PKM | |
| SCHEMBL11051899 | 0.80 | ALDH1A1 (0.47) | LMNAHTTALDH1A1PKMSMN1; SMN2 | |
| SCHEMBL13314764 | 0.79 | TSHR (0.61) | LMNAHTTMAPK1ALDH1A1PKM | |
| SCHEMBL21820680 | 0.79 | ALDH1A1 (0.72) | LMNAHTTMAPK1ALDH1A1PKM | |
| SCHEMBL5696735 | 0.79 | ALDH1A1 (0.72) | LMNAHTTMAPK1ALDH1A1PKM | |
| SCHEMBL223156 | 0.79 | ALDH1A1 (0.72) | LMNAHTTMAPK1ALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5804348-A | COLORLESS, METAL-FREE, IMPROVE CHARGE UNIFORMITY | EASTMAN KODAK COMPANY (US) | 1998-09-08 | — | — | US | claimed |
| EP-0711280-B1 | PERHYDROISOINDOLE DERIVATIVES AS P SUBSTANCE ANTAGONISTS | RHONE POULENC RORER SA (FR) | 1998-09-23 | — | — | EP | disclosed |
| US-5804348-A | COLORLESS, METAL-FREE, IMPROVE CHARGE UNIFORMITY | EASTMAN KODAK COMPANY (US) | 1998-09-08 | — | — | US | disclosed |
| US-5804348-A | COLORLESS, METAL-FREE, IMPROVE CHARGE UNIFORMITY | EASTMAN KODAK COMPANY (US) | 1998-09-08 | — | — | US | disclosed |
| US-5804348-A | COLORLESS, METAL-FREE, IMPROVE CHARGE UNIFORMITY | EASTMAN KODAK COMPANY (US) | 1998-09-08 | — | — | US | disclosed |
| EP-0711280-A1 | PERHYDROISOINDOLE DERIVATIVES AS P SUBSTANCE ANTAGONISTS | Aventis Pharma S.A. (FR) | 1996-05-15 | — | — | EP | disclosed |
| WO-1995004040-A1 | PERHYDROISOINDOLE DERIVATIVES AS P SUBSTANCE ANTAGONISTS | RHONE-POULENC RORER S.A. (FR) | 1995-02-09 | — | — | WO | disclosed |