Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | PKM | P14618 | 6/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9766713 | 0.90 | ALDH1A1 (0.58) | ALDH1A1PKMGAATDP1CYP2C19 | |
| SCHEMBL9067423 | 0.83 | TDP1 (0.55) | ALDH1A1GAATDP1CYP2C19MEN1 | |
| SCHEMBL8658900 | 0.83 | LMNA (0.52) | ALDH1A1PKMGAATDP1MEN1 | |
| SCHEMBL9067743 | 0.80 | CA12 (0.62) | ALDH1A1PKMGAATDP1CYP2C19 | |
| SCHEMBL4703731 | 0.78 | CA12 (0.71) | ALDH1A1PKMGAAMEN1KMT2A | |
| SCHEMBL5435010 | 0.78 | GAA (0.60) | ALDH1A1PKMGAATDP1CYP2C19 | |
| SCHEMBL28079518 | 0.78 | CYP3A4 (0.66) | ALDH1A1PKMGAACYP2C19MEN1 | |
| SCHEMBL812738 | 0.78 | ALDH1A1 (0.75) | ALDH1A1PKMGAATDP1CYP2C19 | |
| SCHEMBL9067555 | 0.76 | ALDH1A1 (0.61) | ALDH1A1TDP1KMT2ALMNAKDM4E | |
| SCHEMBL2009140 | 0.75 | MMP2 (0.61) | ALDH1A1PKMGAALMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5019269-A | Polymers derived from crosslinked polystyrenes and dextrans, their methods of preparation and their applications for the analysis and purification of molecules of biological origin | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 1991-05-28 | — | — | US | disclosed |
| US-4950712-A | ION EXCHANGING AND AFFINITY CHROMATOGRAPHY | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) | 1990-08-21 | — | — | US | disclosed |