SCHEMBL8659115

SCHEMBL8659115

OCCOc1ccc(-n2nnnc2S)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.42
TSHR P16473 4/20 0.42
SMN1; SMN2 Q16637 3/20 0.42
RAB9A P51151 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
NPC1 O15118 1/20 0.42
NFKB1 P19838 1/20 0.42
NFKB2 Q00653 1/20 0.42
RELA Q04206 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
RECQL P46063 1/20 0.41
LMNA P02545 3/20 0.40
PKM P14618 2/20 0.40
HTT P42858 2/20 0.40
NLRP3 Q96P20 1/20 0.40
KMT2A Q03164 2/20 0.40
NPSR1 Q6W5P4 2/20 0.40
MEN1 O00255 1/20 0.40
MAPT P10636 3/20 0.39
NR1I2 O75469 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9769963 0.84 KDM1A (0.44) ALDH1A1TSHRSMN1; SMN2RAB9AL3MBTL1
SCHEMBL3418827 0.81 MAPT (0.56) ALDH1A1TSHRSMN1; SMN2RAB9ANPC1
SCHEMBL12892334 0.81 NR4A1 (0.50) ALDH1A1TSHRSMN1; SMN2TDP1LMNA
SCHEMBL8655762 0.78 ALDH1A1 (0.41) ALDH1A1TSHRSMN1; SMN2L3MBTL1LMNA
SCHEMBL3292317 0.76 PTGS2 (0.51) ALDH1A1TSHRSMN1; SMN2L3MBTL1TDP1
SCHEMBL3298388 0.76 ALDH1A1 (0.55) ALDH1A1TSHRSMN1; SMN2RAB9ANPC1
SCHEMBL3295146 0.76 PTGS2 (0.49) ALDH1A1TSHRSMN1; SMN2L3MBTL1LMNA
SCHEMBL8679056 0.74 MAPK1 (0.43) ALDH1A1TSHRSMN1; SMN2RAB9AL3MBTL1
SCHEMBL594488 0.73 ALDH1A1 (0.47) ALDH1A1SMN1; SMN2L3MBTL1LMNAPKM
SCHEMBL17067843 0.71 THRB (0.40) ALDH1A1TSHRSMN1; SMN2LMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0436027-B1 METHOD OF TREATING SILVER HALIDE PHOTOGRAPHIC MATERIAL FUJI PHOTO FILM CO LTD (JP) 1998-10-14 EP disclosed
US-5780198-A MULTILAYER; CONTAINS A HYDRAZINE NUCLEATING AGENT AND A REDOX COMPOUND CAPABLE OF RELEASING A DEVELOPMENT INHIBITOR WHEN THE REDOX COMPOUND IS OXIDIZED; ULTRAHIGH CONTRAST IMAGE WITH BROAD DOT GRADATION FUJI PHOTO FILM CO., LTD. (JP) 1998-07-14 US disclosed
EP-0442323-B1 Silver halide color reversal photographic material capable of providing interimage effect FUJI PHOTO FILM CO LTD (JP) 1997-10-15 EP disclosed
EP-0420005-B1 High contrast silver halide photographic material FUJI PHOTO FILM CO LTD (JP) 1996-07-10 EP disclosed
EP-0395069-B1 Silver halide photographic materials FUJI PHOTO FILM CO LTD (JP) 1996-07-10 EP disclosed
EP-0335319-B1 Silver halide photographic material FUJI PHOTO FILM CO LTD (JP) 1996-06-05 EP disclosed
EP-0398285-B1 Silver halide photographic materials FUJI PHOTO FILM CO LTD (JP) 1995-09-13 EP disclosed
EP-0393720-B1 Silver halide photographic materials FUJI PHOTO FILM CO LTD (JP) 1995-08-23 EP disclosed
US-5395732-A Silver halide photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1995-03-07 US disclosed
US-5278025-A Silver halide photographic materials for imagewise exposure and development FUJI PHOTO FILM CO., LTD. (JP) 1994-01-11 US disclosed
US-5085971-A Redox system capable of releasing development inhibitor by oxidation and a hydrazine compound FUJI PHOTO FILM CO., LTD. (JP) 1992-02-04 US disclosed
EP-0442323-A2 Silver halide color reversal photographic material capable of providing interimage effect FUJI PHOTO FILM CO., LTD. (JP) 1991-08-21 EP disclosed
EP-0436027-A1 METHOD OF TREATING SILVER HALIDE PHOTOGRAPHIC MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 1991-07-10 EP disclosed
US-5006444-A Silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1991-04-09 US disclosed
EP-0420005-A1 high contrast silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1991-04-03 EP disclosed
EP-0398285-A2 Silver halide photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1990-11-22 EP disclosed
EP-0395069-A2 Silver halide photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1990-10-31 EP disclosed
EP-0393720-A2 Silver halide photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1990-10-24 EP disclosed
EP-0335319-A2 Silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1989-10-04 EP disclosed
US-4737442-A INCLUDING A SENSITIZER AND A BLOCKED DEVELOPMENT RESTRAINER; FREE OF BLACK SPOTS FUJI PHOTO FILM CO., LTD. (JP) 1988-04-12 US disclosed