Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8655147 | 0.91 | CHRM1 (0.32) | SIGMAR1 | |
| SCHEMBL8658143 | 0.89 | SIGMAR1 (0.31) | SIGMAR1 | |
| SCHEMBL8655212 | 0.89 | SIGMAR1 (0.36) | SIGMAR1 | |
| SCHEMBL8654586 | 0.86 | TPSAB1 (0.33) | — | |
| SCHEMBL8659308 | 0.86 | SIGMAR1 (0.35) | SIGMAR1 | |
| SCHEMBL8655554 | 0.84 | GLA (0.30) | — | |
| SCHEMBL8655367 | 0.84 | TPSAB1 (0.33) | — | |
| SCHEMBL8659262 | 0.84 | ACHE (0.43) | — | |
| SCHEMBL8656794 | 0.83 | S1PR5 (0.34) | — | |
| SCHEMBL8661398 | 0.83 | GPR119 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776937-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-07-07 | — | — | US | disclosed |