Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.44 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.41 |
| ▸ | CYTH2 | Q99418 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 5/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ACLY | P53396 | 4/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8663509 | 0.91 | FFAR4 (0.47) | FFAR4KAT6ACYTH2GAAACLY | |
| SCHEMBL8660556 | 0.89 | FFAR4 (0.45) | FFAR4RORCKAT6ACYTH2GAA | |
| SCHEMBL8659487 | 0.89 | FFAR4 (0.45) | FFAR4KAT6ACYTH2GAAALOX15 | |
| SCHEMBL8657903 | 0.88 | PGAM1 (0.45) | FFAR4RORCTSHRHSD17B1HSD17B2 | |
| SCHEMBL8658203 | 0.87 | FFAR4 (0.43) | FFAR4RORCKAT6ACYTH2GAA | |
| SCHEMBL8660309 | 0.86 | FFAR4 (0.45) | FFAR4RORCKAT6ACYTH2GAA | |
| SCHEMBL8656166 | 0.86 | GAA (0.44) | FFAR4KAT6ACYTH2GAATSHR | |
| SCHEMBL8658254 | 0.86 | HSD17B1 (0.43) | FFAR4RORCKAT6ACYTH2GAA | |
| SCHEMBL8659971 | 0.85 | ERAP1 (0.47) | FFAR4KAT6ACYTH2ACLYHSD17B1 | |
| SCHEMBL8660212 | 0.85 | KAT6A (0.45) | FFAR4RORCKAT6ACYTH2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739166-A | ALKYLSULFONYL OR AMINOSULFONYL SUBSTITUTED AROMATIC COMPOUNDS AS NON-STEROIDAL ANTIINFLAMMATORY AGENT | G.D. SEARLE & CO. (US) | 1998-04-14 | — | — | US | disclosed |