Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.43 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.40 |
| ▸ | CYTH2 | Q99418 | 1/20 | 0.39 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.39 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.38 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8663509 | 0.89 | FFAR4 (0.47) | GAAKMT2AFFAR4KAT6ACYTH2 | |
| SCHEMBL8659487 | 0.87 | FFAR4 (0.45) | GAAKMT2AFFAR4KAT6ACYTH2 | |
| SCHEMBL8660556 | 0.87 | FFAR4 (0.45) | GAAKMT2AFFAR4KAT6ACYTH2 | |
| SCHEMBL8659227 | 0.86 | ERAP1 (0.46) | GAAKMT2AFFAR4KAT6AERAP1 | |
| SCHEMBL8660484 | 0.86 | FFAR4 (0.44) | GAAKMT2AFFAR4KAT6ACYTH2 | |
| SCHEMBL8660191 | 0.85 | STAT3 (0.43) | KMT2AFFAR4KAT6ACYTH2TSHR | |
| SCHEMBL8658203 | 0.85 | FFAR4 (0.43) | GAAKMT2AFFAR4KAT6ACYTH2 | |
| SCHEMBL8660309 | 0.84 | FFAR4 (0.45) | GAAKMT2AFFAR4KAT6ACYTH2 | |
| SCHEMBL8657894 | 0.84 | L3MBTL1 (0.44) | GAAKMT2AKAT6ACYTH2SLC40A1 | |
| SCHEMBL8661075 | 0.84 | CYTH2 (0.48) | GAAKMT2AFFAR4KAT6ACYTH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739166-A | ALKYLSULFONYL OR AMINOSULFONYL SUBSTITUTED AROMATIC COMPOUNDS AS NON-STEROIDAL ANTIINFLAMMATORY AGENT | G.D. SEARLE & CO. (US) | 1998-04-14 | — | — | US | disclosed |