Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8659988 | 1.00 | PARP1 (0.55) | PARP1NPC1RAB9ACASP3SENP8 | |
| SCHEMBL2625204 | 0.81 | PARP1 (0.62) | PARP1NPC1RAB9ACASP3SENP8 | |
| SCHEMBL7533265 | 0.79 | MMP1 (0.46) | PARP1NPC1RAB9ACASP3SENP8 | |
| SCHEMBL8664868 | 0.77 | NLN (0.61) | CASP3SENP8SENP7MEN1KMT2A | |
| SCHEMBL8661069 | 0.77 | NLN (0.61) | CASP3SENP8SENP7MEN1KMT2A | |
| SCHEMBL8661068 | 0.77 | NLN (0.61) | CASP3SENP8SENP7MEN1KMT2A | |
| SCHEMBL6622312 | 0.74 | MMP1 (0.52) | PARP1NPC1RAB9ACASP3SENP8 | |
| SCHEMBL18019186 | 0.74 | LARS1 (0.55) | ALDH1A1MMP1ADAM17POLB | |
| SCHEMBL20048653 | 0.74 | LARS1 (0.44) | PARP1NPC1RAB9AMMP1ADAM17 | |
| SCHEMBL11855800 | 0.73 | ALDH1A1 (0.59) | PARP1NPC1RAB9ACASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5804400-A | Electrochemiluminescent assay | IGEN INTERNATIONAL, INC. (US) | 1998-09-08 | — | — | US | disclosed |
| WO-1997028275-A1 | ELECTROCHEMILUMINESCENCE ENZYME ASSAY | IGEN INTERNATIONAL, INC. (US) | 1997-08-07 | — | — | WO | disclosed |