Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 3/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.56 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.56 |
| ▸ | FEN1 | P39748 | 1/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.51 |
| ▸ | PTGES2 | Q9H7Z7 | 3/20 | 0.50 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.50 |
| ▸ | TUBB | P07437 | 1/20 | 0.50 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.50 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.50 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.50 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.50 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.50 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.50 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8658333 | 0.89 | STAT3 (0.59) | STAT3ALOX5APFEN1CA12CA2 | |
| SCHEMBL8662804 | 0.89 | PTGES2 (0.61) | STAT3ALOX5APFEN1CA12CA2 | |
| SCHEMBL8657396 | 0.88 | PTGS2 (0.52) | STAT3PTGS2PTGS1MEN1TSHR | |
| SCHEMBL8658522 | 0.87 | STAT3 (0.74) | STAT3ALOX5APFEN1CA12CA2 | |
| SCHEMBL8648154 | 0.87 | PTGS2 (0.51) | STAT3PTGS2PTGS1 | |
| SCHEMBL8662887 | 0.86 | MCOLN3 (0.54) | STAT3ALOX5APFEN1CA12CA2 | |
| SCHEMBL8660236 | 0.85 | STAT3 (0.56) | STAT3ALOX5APFEN1CA12CA2 | |
| SCHEMBL8657888 | 0.84 | ALDH1A1 (0.61) | STAT3ALOX5APFEN1CA12CA2 | |
| SCHEMBL8661197 | 0.84 | STAT3 (0.62) | STAT3PTGS2ALOX5APFEN1PTGS1 | |
| SCHEMBL8659594 | 0.83 | MCOLN3 (0.48) | STAT3ALOX5APFEN1CA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739166-A | ALKYLSULFONYL OR AMINOSULFONYL SUBSTITUTED AROMATIC COMPOUNDS AS NON-STEROIDAL ANTIINFLAMMATORY AGENT | G.D. SEARLE & CO. (US) | 1998-04-14 | — | — | US | claimed |
| US-5739166-A | ALKYLSULFONYL OR AMINOSULFONYL SUBSTITUTED AROMATIC COMPOUNDS AS NON-STEROIDAL ANTIINFLAMMATORY AGENT | G.D. SEARLE & CO. (US) | 1998-04-14 | — | — | US | disclosed |