Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYTH2 | Q99418 | 2/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | KAT6A | Q92794 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.43 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.43 |
| ▸ | METAP2 | P50579 | 1/20 | 0.43 |
| ▸ | IL1RN | P18510 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8659718 | 0.89 | KAT6A (0.54) | CYTH2FFAR4KAT6ANPSR1TSHR | |
| SCHEMBL8661104 | 0.88 | CYTH2 (0.48) | CYTH2FFAR4NPSR1SLC40A1METAP2 | |
| SCHEMBL8661428 | 0.87 | CYTH2 (0.54) | CYTH2FFAR4KAT6ASLC40A1METAP2 | |
| SCHEMBL8663489 | 0.87 | CYTH2 (0.54) | CYTH2FFAR4KAT6AMETAP2MCL1 | |
| SCHEMBL8660475 | 0.87 | FFAR4 (0.56) | CYTH2FFAR4METAP2MCL1TSHR | |
| SCHEMBL8657558 | 0.87 | ERBB2 (0.47) | CYTH2FFAR4KAT6AGAA | |
| SCHEMBL8658156 | 0.87 | NPSR1 (0.50) | CYTH2FFAR4KAT6ANPSR1KEAP1 | |
| SCHEMBL8657865 | 0.86 | CYTH2 (0.49) | CYTH2FFAR4KAT6AMETAP2MCL1 | |
| SCHEMBL8661364 | 0.86 | KAT6A (0.49) | CYTH2FFAR4KAT6ASLC40A1TSHR | |
| SCHEMBL8661445 | 0.85 | CA12 (0.51) | CYTH2FFAR4METAP2KEAP1MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739166-A | ALKYLSULFONYL OR AMINOSULFONYL SUBSTITUTED AROMATIC COMPOUNDS AS NON-STEROIDAL ANTIINFLAMMATORY AGENT | G.D. SEARLE & CO. (US) | 1998-04-14 | — | — | US | disclosed |