Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.56 |
| ▸ | METAP2 | P50579 | 2/20 | 0.51 |
| ▸ | CYTH2 | Q99418 | 3/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | NAT1 | P18440 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8661445 | 0.90 | CA12 (0.51) | FFAR4METAP2CYTH2MCL1CA12 | |
| SCHEMBL8662846 | 0.89 | MCL1 (0.55) | FFAR4METAP2CYTH2MCL1LMNA | |
| SCHEMBL8663489 | 0.89 | CYTH2 (0.54) | FFAR4METAP2CYTH2MCL1CA12 | |
| SCHEMBL8661428 | 0.89 | CYTH2 (0.54) | FFAR4METAP2CYTH2MCL1TSHR | |
| SCHEMBL8657865 | 0.87 | CYTH2 (0.49) | FFAR4METAP2CYTH2MCL1CA12 | |
| SCHEMBL8661104 | 0.87 | CYTH2 (0.48) | FFAR4METAP2CYTH2MCL1CA12 | |
| SCHEMBL8660183 | 0.87 | CYTH2 (0.48) | FFAR4METAP2CYTH2MCL1TSHR | |
| SCHEMBL8657915 | 0.86 | CYTH2 (0.51) | FFAR4METAP2CYTH2MCL1TSHR | |
| SCHEMBL8657558 | 0.86 | ERBB2 (0.47) | FFAR4CYTH2NAT1 | |
| SCHEMBL8656948 | 0.85 | CYTH2 (0.50) | FFAR4METAP2CYTH2MCL1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739166-A | ALKYLSULFONYL OR AMINOSULFONYL SUBSTITUTED AROMATIC COMPOUNDS AS NON-STEROIDAL ANTIINFLAMMATORY AGENT | G.D. SEARLE & CO. (US) | 1998-04-14 | — | — | US | disclosed |