Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYTH2 | Q99418 | 2/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.46 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.43 |
| ▸ | IL1RN | P18510 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | G6PD | P11413 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8657865 | 0.92 | CYTH2 (0.49) | CYTH2FFAR4METAP2MCL1TSHR | |
| SCHEMBL8661452 | 0.90 | SLC40A1 (0.45) | CYTH2FFAR4SLC40A1METAP2TSHR | |
| SCHEMBL8661174 | 0.89 | CYTH2 (0.43) | CYTH2FFAR4SLC40A1METAP2IL1RN | |
| SCHEMBL8661400 | 0.89 | STAT3 (0.48) | CYTH2FFAR4METAP2IL1RNKEAP1 | |
| SCHEMBL8660183 | 0.88 | CYTH2 (0.48) | CYTH2FFAR4SLC40A1METAP2IL1RN | |
| SCHEMBL8661056 | 0.88 | CYTH2 (0.43) | CYTH2FFAR4METAP2MCL1 | |
| SCHEMBL8660191 | 0.88 | STAT3 (0.43) | CYTH2FFAR4TSHRMEN1KMT2A | |
| SCHEMBL8660475 | 0.87 | FFAR4 (0.56) | CYTH2FFAR4METAP2MCL1TSHR | |
| SCHEMBL8657558 | 0.87 | ERBB2 (0.47) | CYTH2FFAR4MEN1KMT2AHPGD | |
| SCHEMBL8661428 | 0.87 | CYTH2 (0.54) | CYTH2FFAR4SLC40A1METAP2MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739166-A | ALKYLSULFONYL OR AMINOSULFONYL SUBSTITUTED AROMATIC COMPOUNDS AS NON-STEROIDAL ANTIINFLAMMATORY AGENT | G.D. SEARLE & CO. (US) | 1998-04-14 | — | — | US | disclosed |