Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 2/20 | 0.47 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8661264 | 0.91 | STAT3 (0.45) | MCL1STAT3ALDH1A1KMT2ATSHR | |
| SCHEMBL8663461 | 0.89 | PGAM1 (0.48) | STAT3FFAR4SLC40A1ALOX5APFEN1 | |
| SCHEMBL8660960 | 0.87 | MCOLN3 (0.57) | MCL1STAT3ALDH1A1KMT2ATSHR | |
| SCHEMBL8659158 | 0.87 | KIF11 (0.53) | STAT3KMT2AFFAR4GAAKIF11 | |
| SCHEMBL8661208 | 0.87 | STAT3 (0.52) | MCL1STAT3ALDH1A1TSHRFFAR4 | |
| SCHEMBL8659786 | 0.87 | PTGS2 (0.53) | MCL1STAT3ALDH1A1TSHRFFAR4 | |
| SCHEMBL8659319 | 0.86 | PGAM1 (0.47) | STAT3TSHRFFAR4MAPTSLC40A1 | |
| SCHEMBL8659727 | 0.85 | STAT3 (0.50) | STAT3ALDH1A1KMT2AMAPTL3MBTL1 | |
| SCHEMBL8659075 | 0.84 | TSHR (0.56) | MCL1STAT3ALDH1A1TSHRFFAR4 | |
| SCHEMBL8657426 | 0.84 | SCN9A (0.46) | STAT3KMT2ATSHRFFAR4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739166-A | ALKYLSULFONYL OR AMINOSULFONYL SUBSTITUTED AROMATIC COMPOUNDS AS NON-STEROIDAL ANTIINFLAMMATORY AGENT | G.D. SEARLE & CO. (US) | 1998-04-14 | — | — | US | disclosed |