Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 3/20 | 0.50 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ACLY | P53396 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.43 |
| ▸ | TUBB | P07437 | 1/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8661279 | 0.91 | STAT3 (0.50) | STAT3ERAP1HPGDL3MBTL1KMT2A | |
| SCHEMBL8659946 | 0.88 | PTGS2 (0.56) | STAT3HPGDL3MBTL1KMT2AACLY | |
| SCHEMBL8659675 | 0.88 | STAT3 (0.58) | STAT3HPGDL3MBTL1KMT2AACLY | |
| SCHEMBL8663461 | 0.86 | PGAM1 (0.48) | STAT3ERAP1ACLY | |
| SCHEMBL8659494 | 0.85 | PTGS2 (0.58) | STAT3HPGDL3MBTL1KMT2AGAA | |
| SCHEMBL8660195 | 0.85 | MCL1 (0.47) | STAT3L3MBTL1KMT2AGAAACLY | |
| SCHEMBL8660532 | 0.85 | STAT3 (0.58) | STAT3HPGDL3MBTL1ACLYALDH1A1 | |
| SCHEMBL8657407 | 0.84 | PTGS2 (0.59) | STAT3HPGDL3MBTL1KMT2AACLY | |
| SCHEMBL8660126 | 0.84 | STAT3 (0.47) | STAT3ERAP1HPGDL3MBTL1KMT2A | |
| SCHEMBL8659158 | 0.84 | KIF11 (0.53) | STAT3KMT2AGAAACLY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739166-A | ALKYLSULFONYL OR AMINOSULFONYL SUBSTITUTED AROMATIC COMPOUNDS AS NON-STEROIDAL ANTIINFLAMMATORY AGENT | G.D. SEARLE & CO. (US) | 1998-04-14 | — | — | US | disclosed |