Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.47 |
| ▸ | BMX | P51813 | 2/20 | 0.47 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.47 |
| ▸ | BTK | Q06187 | 2/20 | 0.47 |
| ▸ | ITK | Q08881 | 2/20 | 0.47 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.47 |
| ▸ | STAT3 | P40763 | 5/20 | 0.43 |
| ▸ | SYK | P43405 | 2/20 | 0.40 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | BRAF | P15056 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1398283 | 0.81 | BRD4 (0.58) | BRD4BRAF | |
| SCHEMBL750335 | 0.79 | GDA (0.55) | PTK2BTKSTAT3SYKGDA | |
| SCHEMBL31506448 | 0.79 | GDA (0.55) | PTK2BTKSTAT3SYKGDA | |
| SCHEMBL28810103 | 0.77 | CDK2 (0.48) | EGFRBMXPTK2BTKITK | |
| SCHEMBL1358803 | 0.75 | SYK (0.46) | PTK2BTKSTAT3SYKGDA | |
| SCHEMBL1398292 | 0.74 | GDA (0.68) | GDAXDH | |
| SCHEMBL8718988 | 0.74 | SYK (0.46) | PTK2BTKSTAT3SYKGDA | |
| SCHEMBL8121393 | 0.73 | STAT3 (0.69) | BTKSTAT3CDK1BRD4HDAC1 | |
| SCHEMBL8764937 | 0.72 | MAPT (0.48) | STAT3SYKCDK1BRD4XDH | |
| SCHEMBL4452979 | 0.71 | TGM2 (0.46) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0670845-B1 | PROCESS FOR THE PREPARATION OF FLUDARABINE PHOSPHATE FROM GUANOSINE | SCHERING AG (DE) | 1998-01-14 | — | — | EP | disclosed |
| US-5668270-A | Process for the preparation of fludarabine or fludarabine phosphate from guanosine | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-09-16 | — | — | US | disclosed |
| US-5602246-A | Process for the preparation of fludarabine or fludarabine phosphate from guanosine | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-02-11 | — | — | US | disclosed |
| EP-0670845-A1 | PROCESS FOR THE PREPARATION OF FLUDARABINE PHOSPHATE FROM GUANOSINE | SCHERING AKTIENGESELLSCHAFT (DE) | 1995-09-13 | — | — | EP | disclosed |
| WO-1994012514-A1 | PROCESS FOR THE PREPARATION OF FLUDARABINE PHOSPHATE FROM GUANOSINE | SCHERING AKTIENGESELLSCHAFT (DE) | 1994-06-09 | — | — | WO | disclosed |