Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 9/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | NT5C2 | P49902 | 2/20 | 0.53 |
| ▸ | BRAF | P15056 | 2/20 | 0.52 |
| ▸ | NT5E | P21589 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | TOP2A | P11388 | 1/20 | 0.50 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CDK2 | P24941 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22118772 | 0.81 | BRD4 (0.68) | BRD4NPC1RAB9ANT5C2BRAF | |
| SCHEMBL8660442 | 0.81 | EGFR (0.47) | BRD4BRAF | |
| SCHEMBL29475418 | 0.80 | BRAF (0.72) | BRD4NPC1RAB9ANT5C2BRAF | |
| SCHEMBL536913 | 0.80 | BRAF (0.72) | BRD4NPC1RAB9ANT5C2BRAF | |
| SCHEMBL5437612 | 0.80 | BRD4 (0.62) | BRD4NPC1RAB9ANT5C2BRAF | |
| SCHEMBL28669706 | 0.77 | NPC1 (0.63) | BRD4NPC1RAB9ANT5C2BRAF | |
| SCHEMBL28828155 | 0.77 | BRD4 (0.59) | BRD4NPC1RAB9ANT5C2BRAF | |
| SCHEMBL67930 | 0.77 | JAK3 (0.39) | — | |
| SCHEMBL8720615 | 0.76 | BRD4 (0.58) | BRD4NPC1RAB9ANT5C2BRAF | |
| SCHEMBL17362837 | 0.76 | BRD4 (0.58) | BRD4NPC1RAB9ANT5C2BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2764065-B1 | SACRIFICIAL ADHESIVE COATINGS | ROCHAL IND LLC (US) | 2017-03-22 | — | — | EP | claimed |
| US-8263720-B1 | Sacrificial adhesive coatings | ROCHAL INDUSTRIES, LLP (US) | 2012-09-11 | — | — | US | claimed |
| US-11839626-B2 | Composition and kits for inhibition of pathogenic microbial infection and methods of using the same | ROCHAL TECHNOLOGIES LLC (US) | 2023-12-12 | — | — | US | disclosed |
| EP-3220741-B1 | COMPOSITION AND KITS FOR INHIBITION OF PATHOGENIC MICROBIAL INFECTION AND METHODS OF USING THE SAME | ROCHAL IND LLC (US) | 2021-02-24 | — | — | EP | disclosed |
| US-20170360825-A1 | Composition and Kits for Inhibition of Pathogenic Microbial Infection and Methods of Using the Same | ROCHAL INDUSTRIES, LLC (US) | 2017-12-21 | — | — | US | disclosed |
| EP-2764065-B1 | SACRIFICIAL ADHESIVE COATINGS | ROCHAL IND LLC (US) | 2017-03-22 | — | — | EP | disclosed |
| US-20160095876-A1 | COMPOSITION AND KITS FOR INHIBITION OF PATHOGENIC MICROBIAL INFECTION AND METHODS OF USING THE SAME | CRG SERVICING LLC | 2016-04-07 | — | — | US | disclosed |
| EP-2764065-A1 | SACRIFICIAL ADHESIVE COATINGS | Rochal Industries, LLP (US) | 2014-08-13 | — | — | EP | disclosed |
| WO-2013052276-A1 | SACRIFICIAL ADHESIVE COATINGS | ROCHAL INDUSTRIES, LLP (US) | 2013-04-11 | — | — | WO | disclosed |
| US-8263720-B1 | Sacrificial adhesive coatings | ROCHAL INDUSTRIES, LLP (US) | 2012-09-11 | — | — | US | disclosed |
| EP-1968655-B1 | CONFORMABLE BANDAGE AND COATING MATERIAL | ROCHAL IND LLP (US) | 2011-03-02 | — | — | EP | disclosed |
| US-7855285-B2 | Methods for selective N-9 glycosylation of purines | BRIGHAM YOUNG UNIVERSITY (US) | 2010-12-21 | — | — | US | disclosed |
| US-7795326-B2 | Solution of an amphiphilic copolymer of a nitrogen-containing monomer, such as N-isopropylacrylamide, and a siloxy monomer, preferably 3-(methacryloyloxy)propyltris(trimethylsiloxy)silane in non-stinging, volatile, siloxane, alkane, fluorocarbon, lor iquid or supercritical carbon dioxide; medical devices | ROCHAL INDUSTRIES, LLP (US) | 2010-09-14 | — | — | US | disclosed |
| EP-1968655-A2 | CONFORMABLE BANDAGE AND COATING MATERIAL | Rochal Industries, LLP (US) | 2008-09-17 | — | — | EP | disclosed |
| US-20080207891-A1 | Methods For Selective N-9 Glycosylation of Purines | BRIGHAM YOUNG UNIVERSITY (US) | 2008-08-28 | — | — | US | disclosed |
| EP-1895841-A2 | METHODS FOR SELECTIVE N-9 GLYCOSYLATION OF PURINES | Brigham Young University (US) | 2008-03-12 | — | — | EP | disclosed |
| WO-2007067866-A2 | CONFORMABLE BANDAGE AND COATING MATERIAL | ROCHAL INDUSTRIES, LLP (US) | 2007-06-14 | — | — | WO | disclosed |
| US-20070129474-A1 | Solution of an amphiphilic copolymer of a nitrogen-containing monomer, such as N-isopropylacrylamide, and a siloxy monomer, preferably 3-(methacryloyloxy)propyltris(trimethylsiloxy)silane in non-stinging, volatile, siloxane, alkane, fluorocarbon, lor iquid or supercritical carbon dioxide; medical devices | ROCHAL INDUSTRIES, LLP. (US) | 2007-06-07 | — | — | US | disclosed |
| WO-2006138396-A2 | METHODS FOR SELECTIVE N-9 GLYCOSYLATION OF PURINES | BRIGHAM YOUNG UNIVERSITY, TRANSFER TECHNOLOGY OFFICE (US) | 2006-12-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160095876-A1 | COMPOSITION AND KITS FOR INHIBITION OF PATHOGENIC MICROBIAL INFECTION AND METHODS OF USING THE SAME | CUTA, MMP8, MMP1 | BRD4 4803/4885NPC1 1625/4885RAB9A 1093/4885 |
| US-20170360825-A1 | Composition and Kits for Inhibition of Pathogenic Microbial Infection and Methods of Using the Same | CUTA, MMP8, MMP1 | BRD4 4804/4885NPC1 1631/4885RAB9A 1096/4885 |
| US-20080207891-A1 | Methods For Selective N-9 Glycosylation of Purines | PNP, SLC29A2, SLC28A2 | BRD4 4289/4885NPC1 1127/4885RAB9A 882/4885 |
| US-11839626-B2 | Composition and kits for inhibition of pathogenic microbial infection and methods of using the same | CUTA, MMP8, MMP1 | BRD4 4804/4885NPC1 1631/4885RAB9A 1096/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.