Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6931771 | 0.86 | SLC15A1 (0.39) | ATMTAAR1 | |
| SCHEMBL6925970 | 0.82 | SLC15A1 (0.42) | ABCB1MEN1KMT2A | |
| SCHEMBL6931618 | 0.81 | KLK5 (0.48) | ATMCTSBCTSLCTSK | |
| SCHEMBL28233244 | 0.78 | CYP1A2 (0.41) | ATMALDH1A1 | |
| SCHEMBL7273532 | 0.76 | ABCB1 (0.40) | ABCB1CTSBMEN1KMT2AALDH1A1 | |
| SCHEMBL6400372 | 0.75 | OPRK1 (0.40) | ATMCTSBMEN1KMT2ATAAR1 | |
| SCHEMBL4729192 | 0.75 | OPRK1 (0.40) | ATMCTSBMEN1KMT2ATAAR1 | |
| SCHEMBL27507556 | 0.74 | ATM (0.41) | ATMMEN1KMT2AALDH1A1 | |
| SCHEMBL6165008 | 0.74 | TAAR1 (0.38) | L3MBTL1ATMCTSBMEN1KMT2A | |
| SCHEMBL10686536 | 0.74 | CYP1A2 (0.43) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5728718-A | RETROVIRAL PROTEASE INHIBITOR; TREATMENT OF HTLV | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1998-03-17 | — | — | US | disclosed |