SCHEMBL8661034

SCHEMBL8661034

Cc1nc2c(cc1Cl)C(=O)OC2=O

nearest known ligand 0.46

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TYMS P04818 3/20 0.33
ALOX15 P16050 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
CYP1A1 P04798 1/20 0.30
CYP1A2 P05177 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10473035 0.81 ALOX15 (0.34) TYMSALOX15TDP1CYP1A2
SCHEMBL10466294 0.70 MAOB (0.41) ALOX15TDP1
SCHEMBL21543448 0.70 ELANE (0.41) TYMSALOX15TDP1
SCHEMBL79833 0.70 ALOX15 (0.48) TYMSALOX15TDP1CYP1A2
SCHEMBL9750690 0.70 MAPT (0.31)
SCHEMBL11350152 0.70 GRIN2D (0.42) TYMSALOX15TDP1CYP1A1CYP1A2
SCHEMBL10404579 0.68
SCHEMBL8659590 0.67 NSD2 (0.41) TYMSALOX15TDP1
SCHEMBL261649 0.67 S100A4 (0.52) TYMSALOX15TDP1CYP1A2
SCHEMBL30442162 0.67 S100A4 (0.52) TYMSALOX15TDP1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5840904-A Fluoro-pyridine-2,3-dicarboxylic anhydrides which are intermediates for herbicidal pyridine-2,3-dicarboximides BASF AKTIENGESELLSCHAFT (DE) 1998-11-24 US disclosed
US-5679622-A HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1997-10-21 US disclosed