SCHEMBL866170

SCHEMBL866170

COC(=O)C(C)OC(C)=O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.50
ALDH1A1 P00352 4/20 0.45
SMN1; SMN2 Q16637 3/20 0.42
CA14 Q9ULX7 2/20 0.39
CHRM2 P08172 1/20 0.38
CHRM4 P08173 1/20 0.38
CHRM1 P11229 1/20 0.38
TBXA2R P21731 1/20 0.38
CA12 O43570 1/20 0.37
GALR3 O60755 1/20 0.37
MAPT P10636 1/20 0.37
BLM P54132 1/20 0.37
TDP1 Q9NUW8 1/20 0.35
TRPV1 Q8NER1 1/20 0.35
HDAC3 O15379 1/20 0.33
HDAC4 P56524 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC7 Q8WUI4 1/20 0.33
HDAC2 Q92769 1/20 0.33
HDAC10 Q969S8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5864497 1.00 TSHR (0.50) TSHRALDH1A1SMN1; SMN2CA14CHRM2
SCHEMBL18776217 0.95 TSHR (0.46) TSHRALDH1A1SMN1; SMN2CA14CHRM2
SCHEMBL10012464 0.81 SMN1; SMN2 (0.44) TSHRALDH1A1SMN1; SMN2CA14CA12
SCHEMBL8706760 0.81 TSHR (0.52) TSHRALDH1A1SMN1; SMN2CHRM2CHRM4
SCHEMBL7358422 0.81 TSHR (0.52) TSHRALDH1A1SMN1; SMN2CHRM2CHRM4
SCHEMBL2174954 0.80 SMN1; SMN2 (0.39) TSHRALDH1A1SMN1; SMN2CA14CA12
SCHEMBL12431158 0.79 TSHR (0.65) TSHRALDH1A1SMN1; SMN2CA14CHRM2
SCHEMBL10017663 0.79 SMN1; SMN2 (0.42) TSHRALDH1A1SMN1; SMN2CA14CA12
SCHEMBL13741138 0.79 SMN1; SMN2 (0.42) TSHRALDH1A1SMN1; SMN2CA14CA12
SCHEMBL20086719 0.79 TSHR (0.50) TSHRALDH1A1SMN1; SMN2CHRM2CHRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 180 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240199526-A1 METHOD FOR SYNTHESIZING COMPOUND IN WHICH ACETOXYLATION REACTION IS APPLIED TO LACTIC ACID DERIVATIVE HYUNDAI MOTOR COMPANY (KR) 2024-06-20 US claimed
WO-2021257717-A1 METHOD FOR MAKING BIO-BASED ACRYLIC ACID NITTO DENKO CORPORATION (JP) 2021-12-23 WO claimed
US-9573874-B2 Acrylic acid and acrylate ester from lactide process SGA POLYMERS, LLC (US) 2017-02-21 US claimed
US-20160083323-A1 IMPROVED ACRYLIC ACID AND ACRYLATE ESTER FROM LACTIDE PROCESS SGA POLYMERS, LLC (US) 2016-03-24 US claimed
US-9290430-B2 Acrylic acid from lactide and process SGA POLYMERS, LLC (US) 2016-03-22 US claimed
EP-2986588-A2 IMPROVED ACRYLIC ACID AND ACRYLATE ESTER FROM LACTIDE PROCESS SGA Polymers, LLC (US) 2016-02-24 EP claimed
US-20150232404-A1 Acrylic Acid from Lactide and Process SGA POLYMERS LLC (US) 2015-08-20 US claimed
EP-2847160-A1 CONVERSION OF METHYL-2-ACETOXY PROPIONATE TO METHYL ACRYLATE AND ACRYLIC ACID The Procter & Gamble Company (US) 2015-03-18 EP claimed
CN-104321303-A Conversion of methyl-2-acetoxy propionate to methyl acrylate and acrylic acid PROCTER & GAMBLE 2015-01-28 CN claimed
WO-2014172540-A2 IMPROVED ACRYLIC ACID AND ACRYLATE ESTER FROM LACTIDE PROCESS SGA POLYMERS, LLC (US) 2014-10-23 WO claimed
WO-2013169589-A1 CONVERSION OF METHYL-2-ACETOXY PROPIONATE TO METHYL ACRYLATE AND ACRYLIC ACID THE PROCTER & GAMBLE COMPANY (US) 2013-11-14 WO claimed
US-20130296602-A1 Conversion of Methyl-2-Acetoxy Propionate to Methyl Acrylate and Acrylic Acid THE PROCTER & GAMBLE COMPANY 2013-11-07 US claimed
WO-2013036389-A1 ACRYLIC ACID FROM LACTIDE SGA POLYMERS, LLC (US) 2013-03-14 WO claimed
US-20120078004-A1 Acrylic Acid from Lactide and Process SGA POLYMERS, LLC 2012-03-29 US claimed
US-20110319849-A1 ABSORBENT ARTICLE COMPRISING A SYNTHETIC POLYMER DERIVED FROM A RENEWABLE RESOURCE AND METHODS OF PRODUCING SAID ARTICLE THE PROCTER & GAMBLE COMPANY 2011-12-29 US claimed
JP-4367863-A None JP disclosed
US-12032290-B2 Actinic ray-sensitive or radiation-sensitive resin composition, resist film, pattern forming method, and method for manufacturing electronic device FUJIFILM CORPORATION (JP) 2024-07-09 US disclosed
EP-0144118-B1 ALKOXYCARBONYLATION OR CARBONYLATION WITH CO AND ORGANIC HYDROXYL COMPOUND THE STANDARD OIL COMPANY (US) 1987-07-15 EP disclosed
EP-0144118-A1 Alkoxycarbonylation or carbonylation with CO and organic hydroxyl compound THE STANDARD OIL COMPANY (US) 1985-06-12 EP disclosed
US-4500727-A HYDROFORMYLATION; EXTRACTION; SEPARATION; OXIDATION; REACTION WITH METHANOL KURARAY CO., LTD. (JP) 1985-02-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240199526-A1 METHOD FOR SYNTHESIZING COMPOUND IN WHICH ACETOXYLATION REACTION IS APPLIED TO LACTIC ACID DERIVATIVE ALDOA, ADSL, LDHA TSHR 4372/4885ALDH1A1 160/4885SMN1; SMN2 1610/4885
US-20160083323-A1 IMPROVED ACRYLIC ACID AND ACRYLATE ESTER FROM LACTIDE PROCESS MCCC2, ME1, MAT2A TSHR 4554/4885ALDH1A1 358/4885SMN1; SMN2 2760/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.