Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8663801 | 0.86 | HDAC1 (0.49) | DGAT1RAB9AMAPTL3MBTL1POLB | |
| SCHEMBL18053917 | 0.83 | NAPRT (0.53) | DGAT1RAB9AMAPTL3MBTL1PKM | |
| SCHEMBL71884 | 0.81 | DGAT1 (0.68) | DGAT1RAB9AMAPTL3MBTL1PKM | |
| SCHEMBL29723823 | 0.81 | DGAT1 (0.68) | DGAT1RAB9AMAPTL3MBTL1PKM | |
| SCHEMBL5059081 | 0.80 | MAPT (0.55) | RAB9AMAPTGAACYP1A2CYP3A4 | |
| SCHEMBL7079697 | 0.79 | SMN1; SMN2 (0.53) | MAPTPOLBGAACYP1A2CYP3A4 | |
| SCHEMBL20259607 | 0.78 | NPSR1 (0.43) | DGAT1RAB9AMAPTPOLBKDM4E | |
| SCHEMBL28774614 | 0.77 | NAPRT (0.62) | DGAT1RAB9AMAPTL3MBTL1PKM | |
| SCHEMBL30154431 | 0.76 | DGAT1 (0.54) | DGAT1RAB9AMAPTL3MBTL1PKM | |
| SCHEMBL30195936 | 0.76 | DGAT1 (0.54) | DGAT1RAB9AMAPTL3MBTL1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763461-A | ANTIPICORNAVIRAL AGENTS | SANOFI (FR) | 1998-06-09 | — | — | US | disclosed |
| US-5618821-A | VIRICIDES, PICORNAVIRUS | SANOFI, S.A. (FR) | 1997-04-08 | — | — | US | disclosed |
| WO-1995031438-A1 | THERAPEUTIC PHENOXYALKYLHETEROCYCLES | SANOFI WINTHROP, INC. (US) | 1995-11-23 | — | — | WO | disclosed |