Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8662091 | 0.86 | DGAT1 (0.60) | MAPTALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL5059081 | 0.84 | MAPT (0.55) | MAPTALDH1A1KMT2AMEN1RAB9A | |
| SCHEMBL20259607 | 0.82 | NPSR1 (0.43) | MAPTALDH1A1KDM4EDGAT1RAB9A | |
| SCHEMBL659139 | 0.81 | CA12 (0.56) | HDAC1HDAC6MAPTALDH1A1KMT2A | |
| SCHEMBL7713081 | 0.81 | DGAT1 (0.45) | HDAC1HDAC6MAPTALDH1A1KMT2A | |
| SCHEMBL29640466 | 0.81 | L3MBTL1 (0.52) | MAPTALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL6783785 | 0.81 | L3MBTL1 (0.52) | MAPTALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL5086187 | 0.79 | ALDH1A1 (0.50) | MAPTALDH1A1KMT2ARAB9ACA12 | |
| SCHEMBL13943192 | 0.79 | HDAC1 (0.47) | HDAC1HDAC6MAPTKMT2AKDM4E | |
| SCHEMBL27929947 | 0.79 | HCAR2 (0.46) | MAPTALDH1A1KMT2AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763461-A | ANTIPICORNAVIRAL AGENTS | SANOFI (FR) | 1998-06-09 | — | — | US | disclosed |
| US-5618821-A | VIRICIDES, PICORNAVIRUS | SANOFI, S.A. (FR) | 1997-04-08 | — | — | US | disclosed |
| WO-1995031438-A1 | THERAPEUTIC PHENOXYALKYLHETEROCYCLES | SANOFI WINTHROP, INC. (US) | 1995-11-23 | — | — | WO | disclosed |