SCHEMBL866225

SCHEMBL866225

Nc1c(Br)cc(-c2cc(Br)c(N)c(Br)c2)cc1Br

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.65
GAA P10253 1/20 0.65
APEX1 P27695 1/20 0.53
CA1 P00915 4/20 0.50
CA2 P00918 4/20 0.50
CA9 Q16790 4/20 0.50
CA3 P07451 1/20 0.50
GSK3B P49841 1/20 0.42
ALDH1A1 P00352 2/20 0.40
CYP3A4 P08684 2/20 0.40
TP53 P04637 1/20 0.40
TSHR P16473 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
CRHBP P24387 1/20 0.36
CRHR2 Q13324 1/20 0.36
NPSR1 Q6W5P4 1/20 0.33
HKDC1 Q2TB90 1/20 0.33
HTT P42858 1/20 0.32
KMT2A Q03164 1/20 0.32
CTSB P07858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methane SCHEMBL29198072 0.97 MAPT (0.61) MAPTGAAAPEX1CA1CA2
SCHEMBL20573009 0.91 MAPT (0.55) MAPTGAAAPEX1CA1CA2
Formaldehyde SCHEMBL20572548 0.91 MAPT (0.55) MAPTGAAAPEX1CA1CA2
SCHEMBL20573002 0.84 GAA (0.48) MAPTGAAAPEX1CA1CA2
SCHEMBL1491967 0.84 CRHBP (0.60) MAPTGAAAPEX1CA1CA2
SCHEMBL4252439 0.84 MAPT (0.48) MAPTGAAAPEX1CA1CA2
SCHEMBL9324245 0.82 ALDH1A1 (0.46) MAPTGAAAPEX1CA1CA2
SCHEMBL23589563 0.80 MAPT (0.50) MAPTGAAALDH1A1CYP3A4TSHR
SCHEMBL27978295 0.80 GAA (0.44) MAPTGAAAPEX1CA1CA2
SCHEMBL9772902 0.80 CA1 (0.54) MAPTGAAAPEX1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 139 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114805805-A Polyimide with high bonding strength and preparation method and application thereof 中国科学院深圳先进技术研究院 2022-07-29 CN claimed
EP-1799791-B1 PHOTOCROSSLINKABLE MATERIALS ROLIC AG (CH) 2016-01-13 EP claimed
US-7687118-B2 Photocrosslinkable materials ROLIC AG (CH) 2010-03-30 US claimed
US-20080069968-A1 Photocrosslinkable Materials ROLIC AG (CH) 2008-03-20 US claimed
EP-1799791-A1 PHOTOCROSSLINKABLE MATERIALS Rolic AG (CH) 2007-06-27 EP claimed
WO-2006039824-A1 PHOTOCROSSLINKABLE MATERIALS ROLIC AG (CH) 2006-04-20 WO claimed
EP-4721843-A1 GAS SEPARATION MEMBRANE UNIT, GAS SEPARATION SYSTEM, AND METHOD FOR PRODUCING ENRICHED GAS UBE Corporation (JP) 2026-04-08 EP disclosed
EP-4691603-A1 GAS SEPARATION SYSTEM AND METHOD FOR PRODUCING METHANE ENRICHED GAS UBE Corporation (JP) 2026-02-11 EP disclosed
US-20260008003-A1 GAS SEPARATION SYSTEM AND METHOD FOR PRODUCING METHANE-ENRICHED GAS UBE CORP (JP) 2026-01-08 US disclosed
US-20250180952-A1 PHOTOALIGNING MATERIALS Rolic Technologies AG (CH) 2025-06-05 US disclosed
WO-2025100202-A1 POLYIMIDE, AND POLYIMIDE THIN FILM 本州化学工業株式会社 2025-05-15 WO disclosed
EP-4493638-A1 PHOTOALIGNING MATERIALS Rolic Technologies AG (CH) 2025-01-22 EP disclosed
US-20240376267-A1 POLYIMIDE RESIN MATERIAL FOR COLORLESS TRANSPARENT PROCESSED PRODUCT AND NOVEL POLYIMIDE HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2024-11-14 US disclosed
EP-0541510-A2 Wholly aromatic polyamide copolymer TEIJIN LIMITED (JP) 1993-05-12 EP disclosed
US-5112941-A A fluorinated membranes with high selectivity MITSUBISHI KASEI CORPORATION (JP) 1992-05-12 US disclosed
US-5006629-A Excellent heat, fire, chemical resistance; spinning and shaping stability; superior mechanical strength TEIJIN LIMITED (JP) 1991-04-09 US disclosed
EP-0407172-A1 Aromatic polyimide separation membrane MITSUBISHI KASEI CORPORATION (JP) 1991-01-09 EP disclosed
EP-0367535-A1 Wholly aromatic polyamide copolymer TEIJIN LIMITED (JP) 1990-05-09 EP disclosed
US-4144225-A Novel aromatic diamine compounds and flame-resistant polyamide compositions containing said compounds KANEBO, LTD. (JP) 1979-03-13 US disclosed
US-4002584-A LONG CHAIN POLYOL, HALOGENATED AROMATIC DIAMINE, ONE-SHOT REACTION IHARA CHEMICAL KOGYO KABUSHIKI KAISHA (JA) 1977-01-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080069968-A1 Photocrosslinkable Materials PARG, VSIR, IGLV6-57 MAPT 467/4885GAA 2875/4885APEX1 2831/4885
US-20260008003-A1 GAS SEPARATION SYSTEM AND METHOD FOR PRODUCING METHANE-ENRICHED GAS SCO2, MT-CO2, SLC2A4 MAPT 3140/4885GAA 4296/4885APEX1 2653/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.