Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | EPAS1 | Q99814 | 9/20 | 0.38 |
| ▸ | VEGFA | P15692 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.32 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8666601 | 0.81 | PTGS2 (0.40) | PTGS2ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL8779966 | 0.80 | PTGS2 (0.35) | PTGS2ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL8663058 | 0.80 | PTGS2 (0.39) | PTGS2EPAS1VEGFA | |
| SCHEMBL8663128 | 0.80 | KDM4E (0.35) | PTGS2ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL8662003 | 0.76 | PTGS2 (0.32) | PTGS2ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL8662561 | 0.76 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2AKDM4ELMNA | |
| SCHEMBL8664430 | 0.75 | PTGS2 (0.43) | PTGS2ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL8666593 | 0.72 | NPC1 (0.35) | PTGS2ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL8665118 | 0.72 | ALDH1A1 (0.37) | PTGS2ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL9219554 | 0.71 | MCL1 (0.45) | PTGS2ALDH1A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739155-A | Haloalkylthio,-sulfinyl and -sulfonyl arylpyrrole insecticidal and acaricidal agents | AMERICAN CYANAMID CO. (US) | 1998-04-14 | — | — | US | disclosed |
| EP-0549866-B1 | Haloalkylthio, -sulfinyl and -sulfonyl arylpyrrole insecticidal, acaricidal and fungicidal agents | AMERICAN CYANAMID CO (US) | 1997-08-13 | — | — | EP | disclosed |
| US-5484807-A | Haloalkylthio, -sulfinyl and -sulfonyl arylpyrrole insecticidal and acaricidal agents | BASF AKTIENGESELLSCHAFT | 1996-01-16 | — | — | US | disclosed |
| US-5468877-A | FOR PROTECTING CROPS | AMERICAN CYANAMID COMPANY (US) | 1995-11-21 | — | — | US | disclosed |
| US-5306827-A | Haloalkylthio, -sulfinyl and -sulfonyl arylpyrrole insecticidal and acaricidal agents | AMERICAN CYANAMID COMPANY (US) | 1994-04-26 | — | — | US | disclosed |
| US-5284863-A | Haloalkylthio, -sulfinyl and -sulfonyl arylpyrrole fungicidal agents | AMERICAN CYANAMID COMPANY (US) | 1994-02-08 | — | — | US | disclosed |
| EP-0549866-A1 | Haloalkylthio, -sulfinyl and -sulfonyl arylpyrrole insecticidal, acaricidal and fungicidal agents | AMERICAN CYANAMID COMPANY (US) | 1993-07-07 | — | — | EP | disclosed |