Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 8/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
| ▸ | EPAS1 | Q99814 | 6/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | VEGFA | P15692 | 1/20 | 0.32 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8666601 | 0.86 | PTGS2 (0.40) | PTGS2PTGS1CCR2EPAS1KDM4E | |
| SCHEMBL8663128 | 0.85 | KDM4E (0.35) | PTGS2PTGS1CCR2EPAS1KDM4E | |
| SCHEMBL8663058 | 0.85 | PTGS2 (0.39) | PTGS2PTGS1CCR2EPAS1VEGFA | |
| SCHEMBL8666733 | 0.84 | EPAS1 (0.39) | PTGS2PTGS1EPAS1KDM4EMEN1 | |
| SCHEMBL8662561 | 0.80 | ALDH1A1 (0.40) | EPAS1KDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL8662003 | 0.80 | PTGS2 (0.32) | PTGS2PTGS1CCR2EPAS1KDM4E | |
| SCHEMBL8662548 | 0.80 | PTGS2 (0.41) | PTGS2EPAS1KDM4EMEN1ALDH1A1 | |
| SCHEMBL8666107 | 0.79 | EPAS1 (0.40) | PTGS2EPAS1MEN1ALDH1A1LMNA | |
| SCHEMBL8664430 | 0.79 | PTGS2 (0.43) | PTGS2PTGS1CCR2EPAS1MEN1 | |
| SCHEMBL8666593 | 0.76 | NPC1 (0.35) | PTGS2PTGS1CCR2EPAS1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0549866-B1 | Haloalkylthio, -sulfinyl and -sulfonyl arylpyrrole insecticidal, acaricidal and fungicidal agents | AMERICAN CYANAMID CO (US) | 1997-08-13 | — | — | EP | disclosed |
| US-5484807-A | Haloalkylthio, -sulfinyl and -sulfonyl arylpyrrole insecticidal and acaricidal agents | BASF AKTIENGESELLSCHAFT | 1996-01-16 | — | — | US | disclosed |
| US-5468877-A | FOR PROTECTING CROPS | AMERICAN CYANAMID COMPANY (US) | 1995-11-21 | — | — | US | disclosed |
| US-5306827-A | Haloalkylthio, -sulfinyl and -sulfonyl arylpyrrole insecticidal and acaricidal agents | AMERICAN CYANAMID COMPANY (US) | 1994-04-26 | — | — | US | disclosed |
| US-5284863-A | Haloalkylthio, -sulfinyl and -sulfonyl arylpyrrole fungicidal agents | AMERICAN CYANAMID COMPANY (US) | 1994-02-08 | — | — | US | disclosed |
| EP-0549866-A1 | Haloalkylthio, -sulfinyl and -sulfonyl arylpyrrole insecticidal, acaricidal and fungicidal agents | AMERICAN CYANAMID COMPANY (US) | 1993-07-07 | — | — | EP | disclosed |