Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | BCHE | P06276 | 3/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.33 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.33 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CCR8 | P51685 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8668000 | 0.87 | KMT2A (0.37) | KMT2AMEN1BCHECNR2BRPF1 | |
| SCHEMBL8523535 | 0.79 | KMT2A (0.40) | KMT2AMEN1BRPF1ALDH1A1HPGD | |
| SCHEMBL8483686 | 0.79 | CNR1 (0.37) | KMT2AMEN1ALDH1A1POLBMAPT | |
| SCHEMBL8667926 | 0.77 | MEN1 (0.37) | KMT2AMEN1POLBTP53GAA | |
| SCHEMBL8503676 | 0.76 | POLB (0.35) | ALDH1A1HPGDPOLB | |
| Hydrochloric Acid SCHEMBL8663917 | 0.76 | MEN1 (0.36) | KMT2AMEN1POLBTP53GAA | |
| SCHEMBL8501146 | 0.76 | POLB (0.35) | KMT2AMEN1POLB | |
| SCHEMBL8504394 | 0.75 | MEN1 (0.37) | KMT2AMEN1POLBTP53GAA | |
| SCHEMBL8662744 | 0.75 | ACKR3 (0.36) | KMT2AMEN1ACKR3ALDH1A1HPGD | |
| SCHEMBL8486153 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827875-A | PYRROLIDINE DERIVATIVES; ANTIATHEROSCLEROSIS AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-10-27 | — | — | US | disclosed |