Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | PAM | P19021 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8664460 | 0.86 | ALDH1A1 (0.39) | ALDH1A1AKR1B10AKR1B1TDP1GLA | |
| SCHEMBL8661187 | 0.82 | KDM4E (0.40) | TDP1MEN1KMT2A | |
| SCHEMBL4543866 | 0.79 | MEN1 (0.39) | ALDH1A1TDP1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL28089546 | 0.78 | HTR2A (0.38) | ALDH1A1TDP1CYP3A4CYP2C9MAPK1 | |
| SCHEMBL8663585 | 0.78 | ALDH1A1 (0.38) | ALDH1A1CYP3A4CYP2C9MAPK1CYP2C19 | |
| SCHEMBL27620966 | 0.77 | RELA (0.40) | ALDH1A1TDP1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL1395549 | 0.76 | RELA (0.44) | TDP1CYP3A4CYP2C9MAPK1CYP2C19 | |
| SCHEMBL28089554 | 0.74 | NPC1 (0.41) | TDP1CYP3A4CYP2C9MAPK1CYP2C19 | |
| SCHEMBL20719893 | 0.73 | AKR1B10 (0.71) | ALDH1A1AKR1B10AKR1B1TDP1GLA | |
| SCHEMBL20719894 | 0.73 | AKR1B10 (0.71) | ALDH1A1AKR1B10AKR1B1TDP1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852128-A | Acid-labile group protected hydroxystyrene polymers or copolymers thereof and their application to radiation sensitive materials | CLARIANT AG (CH) | 1998-12-22 | — | — | US | disclosed |