Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 3/20 | 0.33 |
| ▸ | PPARG | P37231 | 3/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4543866 | 0.79 | MEN1 (0.39) | ALDH1A1HTR2ALMNANPC1MTOR | |
| SCHEMBL28089546 | 0.78 | HTR2A (0.38) | ALDH1A1HTR2ALMNANPC1MTOR | |
| SCHEMBL8662776 | 0.78 | ALDH1A1 (0.40) | ALDH1A1LMNACYP3A4CYP2C9MAPK1 | |
| SCHEMBL27620966 | 0.77 | RELA (0.40) | ALDH1A1LMNANPC1MTORTP53 | |
| SCHEMBL8664460 | 0.76 | ALDH1A1 (0.39) | ALDH1A1HTTLMNANPC1CYP3A4 | |
| SCHEMBL1395549 | 0.76 | RELA (0.44) | HTR2APPARGLMNANPC1MTOR | |
| SCHEMBL28089554 | 0.74 | NPC1 (0.41) | HTR2ALMNANPC1MTORTP53 | |
| SCHEMBL28089544 | 0.73 | HTR2A (0.42) | HTR2APPARGLMNANPC1MTOR | |
| SCHEMBL8661187 | 0.72 | KDM4E (0.40) | PPARG | |
| SCHEMBL6042296 | 0.71 | SIGMAR1 (0.42) | CYP24A1HTR2APPARGNFE2L2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852128-A | Acid-labile group protected hydroxystyrene polymers or copolymers thereof and their application to radiation sensitive materials | CLARIANT AG (CH) | 1998-12-22 | — | — | US | disclosed |