SCHEMBL8662853

SCHEMBL8662853

CN(C)Sc1nc2ccccc2s1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.63
FBP1 P09467 3/20 0.63
HSD17B10 Q99714 3/20 0.63
ADRA2A P08913 1/20 0.63
ADORA3 P0DMS8 1/20 0.63
DRD2 P14416 1/20 0.63
HPGD P15428 1/20 0.63
ALOX15 P16050 1/20 0.63
ADRA2B P18089 1/20 0.63
ADRA2C P18825 1/20 0.63
DRD1 P21728 1/20 0.63
MC5R P33032 1/20 0.63
OPRM1 P35372 1/20 0.63
DRD3 P35462 1/20 0.63
OPRK1 P41145 1/20 0.63
CCR2 P41597 1/20 0.63
HTR6 P50406 1/20 0.63
SLC6A3 Q01959 1/20 0.63
PDK1 Q15118 1/20 0.63
TDP1 Q9NUW8 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29494847 1.00 ALDH1A1 (0.63) ALDH1A1FBP1HSD17B10ADRA2AADORA3
SCHEMBL1193937 0.83 FBP1 (0.56) ALDH1A1FBP1HSD17B10ADRA2AADORA3
SCHEMBL13827005 0.83 FBP1 (0.58) ALDH1A1FBP1HSD17B10ADRA2AADORA3
SCHEMBL11747152 0.82 ALDH1A1 (0.70) ALDH1A1FBP1HSD17B10ADRA2AADORA3
SCHEMBL11767039 0.82 ALOX5 (0.58) ALDH1A1FBP1HSD17B10ADRA2AADORA3
SCHEMBL29494838 0.81 FBP1 (0.59) ALDH1A1FBP1HSD17B10ADRA2AADORA3
SCHEMBL9701728 0.81 ALDH1A1 (0.58) ALDH1A1FBP1HSD17B10ADRA2AADORA3
SCHEMBL78239 0.81 ALDH1A1 (0.58) ALDH1A1FBP1HSD17B10ADRA2AADORA3
SCHEMBL29380841 0.81 ALDH1A1 (0.58) ALDH1A1FBP1HSD17B10ADRA2AADORA3
SCHEMBL11704481 0.81 ALDH1A1 (0.58) ALDH1A1FBP1HSD17B10ADRA2AADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5663358-A Process for the preparation of organosilicon disulfide compounds THE GOODYEAR TIRE & RUBBER COMPANY (US) 1997-09-02 US claimed
EP-0785206-A1 Process for the preparation of organosilicon disulfide compounds THE GOODYEAR TIRE & RUBBER COMPANY (US) 1997-07-23 EP claimed
US-12415907-B2 Rubber composition and run-flat tire BRIDGESTONE CORPORATION (JP) 2025-09-16 US disclosed
US-20250001805-A1 PNEUMATIC TIRE BRIDGESTONE CORPORATION (JP) 2025-01-02 US disclosed
EP-4434766-A1 PNEUMATIC TIRE Bridgestone Corporation (JP) 2024-09-25 EP disclosed
EP-4419583-A1 METHOD FOR PREPARING A RUBBER COMPOSITION COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2024-08-28 EP disclosed
WO-2024024531-A1 METHOD FOR VULCANIZING RUBBER LAMINATE FOR TIRE AND METHOD FOR MANUFACTURING RETREADED TIRE 株式会社ブリヂストン 2024-02-01 WO disclosed
WO-2023228463-A1 METHOD FOR PRODUCING RUBBER COMPOSITION, RUBBER COMPOSITION AND TIRE 株式会社ブリヂストン 2023-11-30 WO disclosed
EP-3677438-B1 PNEUMATIC TIRE BRIDGESTONE CORP (JP) 2023-11-15 EP disclosed
US-20230331880-A1 RUBBER COMPOSITION, RUBBER COMPOSITION FOR TIRES, VULCANIZED RUBBER, RUBBER-METAL COMPOSITE, TIRE, INDUSTRIAL BELT, CRAWLER, AND HOSE BRIDGESTONE CORPORATION (JP) 2023-10-19 US disclosed
EP-4223554-A1 RUBBER COMPOSITION, RUBBER COMPOSITION FOR TIRES, VULCANIZED RUBBER, RUBBER-METAL COMPOSITE, TIRE, INDUSTRIAL BELT, CRAWLER, AND HOSE BRIDGESTONE CORPORATION (JP) 2023-08-09 EP disclosed
US-5760110-A Process for the preparation of a particular reinforced rubber composition THE GOODYEAR TIRE & RUBBER COMPANY (US) 1998-06-02 US disclosed
EP-0794221-A1 Process for the preparation of a particulate reinforced rubber composition THE GOODYEAR TIRE & RUBBER COMPANY (US) 1997-09-10 EP disclosed
US-5663358-A Process for the preparation of organosilicon disulfide compounds THE GOODYEAR TIRE & RUBBER COMPANY (US) 1997-09-02 US disclosed
EP-0785206-A1 Process for the preparation of organosilicon disulfide compounds THE GOODYEAR TIRE & RUBBER COMPANY (US) 1997-07-23 EP disclosed
US-4238615-A FOR USE IN PERFUMES OTSUKA KAGAKU YAKUHIN KABUSHIKI KAISHA (JP) 1980-12-09 US disclosed
US-4182873-A AMINATION OF MERCAPTO THIAZOLE OR DISULFIDE RHONE-POULENC S.A. (FR) 1980-01-08 US disclosed
US-4017506-A Process for the preparation of 2-benzo thiazole sulphinamides UGINE KUHLMANN (FR) 1977-04-12 US disclosed
US-4006140-A AGING RESISTANCE IMPROVERS FOR VULCANIZABLE RUBBERS THE B. F. GOODRICH COMPANY (US) 1977-02-01 US disclosed
US-3976769-A INSECTICIDE AIRWICK INDUSTRIES, INC. (US) 1976-08-24 US disclosed