SCHEMBL8663299

SCHEMBL8663299

Oc1ccccc1-c1cccc(S)c1-c1ccccc1O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.43
HPGD P15428 7/20 0.43
HSD17B10 Q99714 7/20 0.43
BCL2L1 Q07817 1/20 0.43
MAPT P10636 6/20 0.40
MAOA P21397 5/20 0.40
MEN1 O00255 4/20 0.40
KMT2A Q03164 4/20 0.40
ALOX15 P16050 6/20 0.39
TDP1 Q9NUW8 5/20 0.39
SMN1; SMN2 Q16637 4/20 0.39
MAPK1 P28482 4/20 0.39
LMNA P02545 3/20 0.39
MAOB P27338 2/20 0.39
TSHR P16473 1/20 0.39
HTT P42858 1/20 0.39
CA2 P00918 3/20 0.38
CA1 P00915 2/20 0.38
CA7 P43166 1/20 0.38
CA9 Q16790 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4390436 0.84 ALDH1A1 (0.52) ALDH1A1HPGDHSD17B10BCL2L1MAPT
SCHEMBL7148992 0.81 HPGD (0.50) ALDH1A1HPGDHSD17B10BCL2L1MAPT
SCHEMBL29455667 0.81 MAOA (0.52) ALDH1A1HPGDHSD17B10BCL2L1MAPT
SCHEMBL29469517 0.81 MAOA (0.52) ALDH1A1HPGDHSD17B10BCL2L1MAPT
SCHEMBL31534010 0.79 MAOA (0.50) ALDH1A1HPGDHSD17B10BCL2L1MAPT
SCHEMBL31623901 0.79 MAOA (0.50) ALDH1A1HPGDHSD17B10BCL2L1MAPT
SCHEMBL28881715 0.79 HPGD (0.48) ALDH1A1HPGDHSD17B10BCL2L1MAPT
SCHEMBL6660350 0.79 MAPT (0.41) ALDH1A1HSD17B10MAPTMAOAMEN1
SCHEMBL9739116 0.77 SMN1; SMN2 (0.42) ALDH1A1HPGDHSD17B10BCL2L1MAPT
SCHEMBL2729251 0.76 MAOA (0.56) ALDH1A1HPGDHSD17B10BCL2L1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0384665-B1 Optical recording medium JUJO PAPER CO LTD (JP) 1998-10-14 EP disclosed
EP-0381492-B1 Optical recording medium, optical recording method, and optical recording device used in method JUJO PAPER CO LTD (JP) 1998-04-15 EP disclosed
US-5234797-A Photothermic material having a color developing layer of particles comprising a heat-developable material and a heat-emitting light absorbent in a solvent of heat fusible material; lasers; high density image JUJO PAPER CO., LTD. (JP) 1993-08-10 US disclosed
US-5200947-A Laser beam irradiation; hydrophilic substrate,light absorbing layer and heat-sensitive color developing layer JUJO PAPER CO., LTD. (JP) 1993-04-06 US disclosed
US-5100711-A Heat sensitive, colorless basic dyes, paper substrate, infrared radiation JUJO PAPER CO., LTD. (JP) 1992-03-31 US disclosed
EP-0384665-A2 Optical recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1990-08-29 EP disclosed
EP-0381492-A2 Optical recording medium, optical recording method, and optical recording device used in method NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1990-08-08 EP disclosed