Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34937 | 0.89 | LTA4H (0.37) | LTA4HTP53PIN1MAPTHTT | |
| SCHEMBL63205 | 0.87 | ALDH1A1 (0.40) | NPC1ALDH1A1RAB9ASMN1; SMN2TSHR | |
| Phosphine SCHEMBL23931373 | 0.86 | LTA4H (0.35) | LTA4HTP53PIN1MAPTHTT | |
| SCHEMBL712057 | 0.86 | ESR1 (0.37) | LTA4HTP53PIN1MAPTHTT | |
| SCHEMBL28187676 | 0.86 | LTA4H (0.35) | LTA4HTP53PIN1MAPTHTT | |
| SCHEMBL28953919 | 0.85 | ALDH1A1 (0.43) | LTA4HMAPTHTTNPSR1ALDH1A1 | |
| SCHEMBL295849 | 0.84 | LTA4H (0.34) | LTA4HTP53PIN1MAPTHTT | |
| SCHEMBL15847957 | 0.84 | HPGD (0.36) | KDM4EALDH1A1HPGDTSHR | |
| SCHEMBL3301397 | 0.83 | TSHR (0.33) | LTA4HTP53PIN1MAPTHTT | |
| SCHEMBL8465532 | 0.82 | GLA (0.30) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641820-B1 | Organosilicon polymer and process for the preparation thereof | TOSHIBA SILICONE (JP) | 1998-08-12 | — | — | EP | disclosed |
| US-5489662-A | Process for the preparation of organosilicon polymer | TOSHIBA SILICONE CO., LTD. (JP) | 1996-02-06 | — | — | US | disclosed |
| EP-0641820-A1 | Process for the preparation of organosilicon polymer | TOSHIBA SILICONE CO., LTD. (JP) | 1995-03-08 | — | — | EP | disclosed |