Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | ATG7 | O95352 | 13/20 | 0.37 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.37 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.37 |
| ▸ | PI4KA | P42356 | 1/20 | 0.37 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.37 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.37 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL866604 | 0.83 | PI4KA (0.50) | RXFP1P2RX1P2RX3P2RX4PI4KA | |
| SCHEMBL866845 | 0.81 | ATG7 (0.51) | ATG7 | |
| SCHEMBL866897 | 0.79 | RXFP1 (0.48) | CA2CA1CA9RXFP1ATG7 | |
| SCHEMBL14041559 | 0.73 | RXFP1 (0.36) | CA2CA1CA9RXFP1APOBEC3G | |
| SCHEMBL12379249 | 0.72 | RXFP1 (0.86) | RXFP1P2RX1P2RX3P2RX4PI4KA | |
| SCHEMBL2292456 | 0.72 | RXFP1 (0.86) | RXFP1P2RX1P2RX3P2RX4PI4KA | |
| SCHEMBL18522114 | 0.70 | HIF1A (0.41) | RXFP1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL2290806 | 0.69 | RXFP1 (0.61) | CA2CA1CA9RXFP1ATG7 | |
| SCHEMBL20142322 | 0.69 | ATG7 (0.70) | RXFP1ATG7 | |
| SCHEMBL22381736 | 0.68 | P2RX3 (0.47) | P2RX1P2RX3P2RX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120077814-A1 | SULFONAMIDE, SULFAMATE, AND SULFAMOTHIOATE DERIVATIVES | WANG ZHONG (US) | 2012-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120077814-A1 | SULFONAMIDE, SULFAMATE, AND SULFAMOTHIOATE DERIVATIVES | NEDD8, NAE1, UBA3 | CA2 1864/4885CA1 1182/4885CA9 1038/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.