Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | NSD2 | O96028 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8997930 | 0.83 | MAPT (0.43) | KMT2AMEN1MAPTNPC1RAB9A | |
| SCHEMBL8664832 | 0.82 | HTR2A (0.43) | KMT2AMEN1MAPTNPC1RAB9A | |
| SCHEMBL8665476 | 0.78 | ALDH1A1 (0.43) | KMT2AMEN1MAPTNPC1RAB9A | |
| SCHEMBL8663809 | 0.76 | KMT2A (0.43) | KMT2AMEN1MAPTNPC1RAB9A | |
| SCHEMBL8997879 | 0.76 | MAPT (0.43) | KMT2AMEN1MAPTNPC1RAB9A | |
| SCHEMBL17628666 | 0.71 | NPC1 (0.44) | KMT2AMEN1MAPTNPC1RAB9A | |
| SCHEMBL136220 | 0.71 | LMNA (0.52) | KMT2AMEN1MAPTNPC1RAB9A | |
| SCHEMBL30719587 | 0.71 | LMNA (0.52) | KMT2AMEN1MAPTNPC1RAB9A | |
| SCHEMBL8666226 | 0.70 | NPC1 (0.41) | KMT2AMEN1MAPTNPC1RAB9A | |
| SCHEMBL8663997 | 0.70 | KMT2A (0.46) | KMT2AMEN1MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852006-A | N-aminoalkyl-substituted nitrogen-containing six membered heterocyclic compounds | NIPPON CHEMIPHAR CO., LTD. (JP) | 1998-12-22 | — | — | US | disclosed |
| US-5574030-A | INHIBITING URINARY CONTRACTION, HETEROCYCLIC DIAMINES | NIPPON CHEMIPHAR CO., LTD. (JP) | 1996-11-12 | — | — | US | disclosed |