Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.38 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8664016 | 0.83 | KMT2A (0.43) | MAPTL3MBTL1MEN1NPC1RAB9A | |
| SCHEMBL8664832 | 0.82 | HTR2A (0.43) | MAPTL3MBTL1MEN1NPC1RAB9A | |
| SCHEMBL8997879 | 0.82 | MAPT (0.43) | MAPTL3MBTL1MEN1NPC1RAB9A | |
| SCHEMBL8665476 | 0.78 | ALDH1A1 (0.43) | MAPTL3MBTL1MEN1NPC1RAB9A | |
| SCHEMBL4979249 | 0.73 | AKR1C3 (0.67) | MAPTL3MBTL1MEN1NPC1RAB9A | |
| SCHEMBL17628666 | 0.71 | NPC1 (0.44) | MAPTL3MBTL1MEN1NPC1RAB9A | |
| Ammonia Solution, Strong SCHEMBL6931896 | 0.71 | AKR1C3 (0.65) | MAPTL3MBTL1MEN1NPC1RAB9A | |
| SCHEMBL8997898 | 0.70 | MAPT (0.46) | MAPTL3MBTL1MEN1NPC1RAB9A | |
| SCHEMBL9424119 | 0.69 | LMNA (0.62) | MAPTL3MBTL1MEN1NPC1RAB9A | |
| SCHEMBL15362290 | 0.69 | HTR7 (0.62) | MAPTL3MBTL1MEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5574030-A | INHIBITING URINARY CONTRACTION, HETEROCYCLIC DIAMINES | NIPPON CHEMIPHAR CO., LTD. (JP) | 1996-11-12 | — | — | US | disclosed |