Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | HTR5A | P47898 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8664016 | 0.82 | KMT2A (0.43) | ARNPC1RAB9AMEN1MAPT | |
| SCHEMBL8997930 | 0.82 | MAPT (0.43) | NPC1RAB9AMEN1MAPTKMT2A | |
| SCHEMBL8665476 | 0.82 | ALDH1A1 (0.43) | ARNPC1RAB9AMEN1MAPT | |
| SCHEMBL15362290 | 0.81 | HTR7 (0.62) | HTR2AHTR1AHTR7HTR5AHTR6 | |
| SCHEMBL8664502 | 0.79 | AR (0.47) | ARNPC1RAB9APDE4AMAPT | |
| SCHEMBL8997879 | 0.78 | MAPT (0.43) | ARNPC1RAB9AMEN1MAPT | |
| SCHEMBL8663981 | 0.73 | PDE4A (0.42) | HTR2AHTR1AHTR7HTR5AHTR6 | |
| SCHEMBL17628666 | 0.70 | NPC1 (0.44) | HTR7ARNPC1RAB9AMEN1 | |
| SCHEMBL9424119 | 0.68 | LMNA (0.62) | NPC1RAB9APDE4AMEN1MAPT | |
| SCHEMBL21788597 | 0.67 | SMN1; SMN2 (0.59) | ARNPC1PDE4AMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852006-A | N-aminoalkyl-substituted nitrogen-containing six membered heterocyclic compounds | NIPPON CHEMIPHAR CO., LTD. (JP) | 1998-12-22 | — | — | US | disclosed |
| US-5574030-A | INHIBITING URINARY CONTRACTION, HETEROCYCLIC DIAMINES | NIPPON CHEMIPHAR CO., LTD. (JP) | 1996-11-12 | — | — | US | disclosed |