SCHEMBL866412

SCHEMBL866412

O=[N+](O)c1ccc(OS(=O)(=O)[O-])cc1

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA2 P00918 5/20 0.47
CA9 Q16790 3/20 0.47
CA1 P00915 3/20 0.47
PTGS2 P35354 2/20 0.46
HTT P42858 2/20 0.40
CA12 O43570 1/20 0.40
ALDH1A1 P00352 2/20 0.38
HSP90AA1 P07900 1/20 0.38
CISD1 Q9NZ45 1/20 0.37
F11 P03951 3/20 0.36
CES2 O00748 1/20 0.35
CES1 P23141 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
LMNA P02545 1/20 0.35
RECQL P46063 1/20 0.34
HPGD P15428 1/20 0.33
RAB9A P51151 1/20 0.33
STS P08842 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL3198740 0.96 CA2 (0.44) CA2CA9CA1PTGS2HTT
Potassium Ion SCHEMBL1902294 0.80 CA1 (0.67) CA2CA9CA1PTGS2HTT
SCHEMBL31634023 0.80 CA1 (0.67) CA2CA9CA1HTTCA12
Potassium Ion SCHEMBL306657 0.72 PTGS2 (0.65) CA2CA9CA1PTGS2CA12
Zinc Ion SCHEMBL28254385 0.72 PTGS2 (0.59) CA2CA9CA1PTGS2CA12
SCHEMBL2818769 0.72 CISD1 (0.61) CA2CA9CA1PTGS2CA12
SCHEMBL6209548 0.72 CA2 (0.42) CA2CA9CA1CA12ALDH1A1
Tetramethylammonium Ion SCHEMBL4624325 0.72 PTGS2 (0.48) CA2CA9CA1PTGS2CISD1
SCHEMBL9655472 0.71 ALDH1A1 (0.42) ALDH1A1SMN1; SMN2LMNAHPGD
SCHEMBL14406394 0.70 CA1 (0.52) CA2CA9CA1CA12ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 374 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250290051-A1 MUTATED SULFOTRANSFERASES AND USES THEREOF SANOFI SA (FR) 2025-09-18 US claimed
US-20250012802-A1 SYSTEMS AND METHODS FOR PREDICTING RESPONSE TO ORAL MINOXIDIL FOR THE TREATMENT OF ANDROGENETIC ALOPECIA FOLLEA INTERNATIONAL 2025-01-09 US claimed
EP-4488388-A1 SYSTEMS AND METHODS FOR PREDICTING RESPONSE TO ORAL MINOXIDIL FOR THE TREATMENT OF ANDROGENETIC ALOPECIA Follea International (US) 2025-01-08 EP claimed
CN-119265294-A Methods and systems for predicting the response of oral minoxidil to treatment of androgenic alopecia 芙丽亚国际公司 2025-01-07 CN claimed
CN-118339282-A Use and method of sulfating a substrate with a mutated arylsulftransferase 赛诺菲 2024-07-12 CN claimed
US-20240093166-A1 ENGINEERED ARYL SULFATE-DEPENDENT ENZYMES GINKGO BIOWORKS, INC. 2024-03-21 US claimed
US-20240076634-A1 ENGINEERED ARYL SULFATE-DEPENDENT ENZYMES GINKGO BIOWORKS, INC. 2024-03-07 US claimed
US-20240002819-A1 ENGINEERED ARYL SULFATE-DEPENDENT ENZYMES GINKGO BIOWORKS, INC. 2024-01-04 US claimed
US-20230340552-A1 METHODS FOR SYNTHESIZING ANTICOAGULANT POLYSACCHARIDES GINKGO BIOWORKS, INC. 2023-10-26 US claimed
US-11773382-B2 Engineered aryl sulfate-dependent enzymes OPTIMVIA, LLC (US) 2023-10-03 US claimed
EP-2084294-A2 STERILIZATION INDICATOR American Sterilizer Company (US) 2009-08-05 EP claimed
EP-2084293-A2 GENETICALLY ENGINEERED BIOLOGICAL INDICATOR American Sterilizer Company (US) 2009-08-05 EP claimed
US-20090117603-A1 STERILIZATION INDICATOR FRANCISKOVICH PHILLIP P 2009-05-07 US claimed
WO-2008082728-A2 STERILIZATION INDICATOR AMERICAN STERILIZER COMPANY (US) 2008-07-10 WO claimed
WO-2008079469-A2 GENETICALLY ENGINEERED BIOLOGICAL INDICATOR AMERICAN STERILIZER COMPANY (US) 2008-07-03 WO claimed
US-20080070231-A1 Reporter genes taken up by microorganism, and repressor gene inhibits expression AMERICAN STERILIZER COMPANY 2008-03-20 US claimed
US-20080070272-A1 STERILIZATION INDICATOR AMERICAN STERILIZER COMPANY 2008-03-20 US claimed
US-20050255562-A1 Methods for synthesis of sulfated saccharides NATIONAL INSTITUTES OF HEALTH 2005-11-17 US claimed
US-6255088-B1 Enzymatic sulfation of biomolecules THE SCRIPPS RESEARCH INSTITUTE 2001-07-03 US claimed
US-5500668-A INK JET PRINTING XEROX CORPORATION (US) 1996-03-19 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230340552-A1 METHODS FOR SYNTHESIZING ANTICOAGULANT POLYSACCHARIDES CSGALNACT1, NANS, STS CA2 1650/4885CA9 776/4885CA1 1261/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.