Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | HSPB1 | P04792 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9655466 | 0.78 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2AHSPB1MAPT | |
| SCHEMBL9655475 | 0.78 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2AHSPB1MAPT | |
| SCHEMBL9655460 | 0.77 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2AHSPB1MAPT | |
| SCHEMBL6041199 | 0.74 | CA1 (0.41) | ALDH1A1MEN1KMT2AHSPB1MAPT | |
| SCHEMBL27527530 | 0.73 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2AHSPB1MAPT | |
| SCHEMBL8616810 | 0.71 | HSPB1 (0.51) | ALDH1A1MEN1KMT2AHSPB1MAPT | |
| SCHEMBL18218196 | 0.71 | TDP1 (0.74) | ALDH1A1MEN1KMT2AMAPTMAPK1 | |
| SCHEMBL866412 | 0.71 | CA2 (0.47) | ALDH1A1HPGDSMN1; SMN2LMNA | |
| Sulfuric Acid SCHEMBL30951749 | 0.70 | MEN1 (0.54) | ALDH1A1MEN1KMT2AHSPB1MAPT | |
| SCHEMBL16859704 | 0.70 | MEN1 (0.38) | ALDH1A1MEN1KMT2AHSPB1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226516-B1 | AMIDE DERIVATIVES AND ANTIALLERGIC AGENTS CONTAINING THE SAME | TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION (JP) | 1992-07-29 | — | — | EP | disclosed |
| US-4906631-A | Amide derivatives and antiallergic agents containing the same | TERUMO KABUSHIKI KAISHA (JP) | 1990-03-06 | — | — | US | disclosed |
| US-4859673-A | Amide derivatives and antiallergic agents containing the same | TERUMO KABUSHIKI KAISHA (JP) | 1989-08-22 | — | — | US | disclosed |
| US-4795752-A | Amide derivatives and antiallergic agents containing the same | TERUMO KABUSHIKI KAISHA (JP) | 1989-01-03 | — | — | US | disclosed |
| EP-0244319-A2 | Amide derivatives and antiallergic agents containing the same | TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION (JP) | 1987-11-04 | — | — | EP | disclosed |
| EP-0226516-A2 | Amide derivatives and antiallergic agents containing the same | TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION (JP) | 1987-06-24 | — | — | EP | disclosed |