Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.53 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.43 |
| ▸ | HTR3B | O95264 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.43 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24670541 | 0.86 | MAPKAPK2 (0.57) | MAPKAPK2ALDH1A1HSD17B10USP2TSHR | |
| SCHEMBL12814351 | 0.84 | ITGB3 (0.62) | ITGB3ITGA2BALDH1A1HSD17B10USP2 | |
| SCHEMBL8663767 | 0.81 | MAPT (0.50) | ITGB3ITGA2BALDH1A1TSHRMAPT | |
| SCHEMBL8662466 | 0.80 | MAPT (0.61) | ITGB3ITGA2BMAPKAPK2ALDH1A1HSD17B10 | |
| Hydrochloric Acid SCHEMBL9409454 | 0.79 | MAPT (0.60) | ITGB3ITGA2BMAPKAPK2ALDH1A1HSD17B10 | |
| SCHEMBL8325106 | 0.78 | ITGB3 (0.55) | ITGB3ITGA2BALDH1A1HSD17B10USP2 | |
| SCHEMBL8662762 | 0.77 | ITGB3 (0.54) | ITGB3ITGA2BALDH1A1HSD17B10USP2 | |
| SCHEMBL8662766 | 0.77 | ITGB3 (0.54) | ITGB3ITGA2BALDH1A1HSD17B10USP2 | |
| Hydrochloric Acid SCHEMBL8590243 | 0.77 | OGA (0.36) | ITGB3ITGA2BMAPKAPK2ALDH1A1NR4A1 | |
| SCHEMBL14922265 | 0.75 | ADRB1 (0.57) | ITGB3ITGA2BALDH1A1HSD17B10USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5854245-A | Fibrinogen receptor antagonists | MERCK & CO., INC. (US) | 1998-12-29 | — | — | US | disclosed |