Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 6/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL8716555 | 0.96 | PTGIR (0.46) | PTGIRHTR2ACHRM3ACHEKCNH2 | |
| Maleic Acid SCHEMBL8716551 | 0.96 | PTGIR (0.46) | PTGIRHTR2ACHRM3ACHEKCNH2 | |
| SCHEMBL8710951 | 0.93 | SLC18A3 (0.50) | HTR2AACHE | |
| SCHEMBL8710974 | 0.87 | PTGIR (0.47) | PTGIRHTR2ACHRM3ACHEKCNH2 | |
| SCHEMBL8711151 | 0.87 | HTR2A (0.57) | PTGIRHTR2ACHRM3ACHEKCNH2 | |
| SCHEMBL8710869 | 0.84 | ACHE (0.56) | PTGIRHTR2AACHE | |
| SCHEMBL8711207 | 0.84 | LMNA (0.49) | HTR2A | |
| Fumaric Acid SCHEMBL8711104 | 0.84 | PTGIR (0.44) | PTGIRHTR2ACHRM3ACHE | |
| Fumaric Acid SCHEMBL8711107 | 0.84 | PTGIR (0.44) | PTGIRHTR2ACHRM3ACHE | |
| SCHEMBL8711319 | 0.83 | SLC18A3 (0.49) | HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-10077271-A | — | — | None | — | — | JP | disclosed |
| JP-H1077271-A | CIRCULATORY ORGAN MEDICINE CONTAINING 3-PYRIDYLAMINO COMPOUND OR ITS SALT | TOA EIYOO KK | 1998-03-24 | — | — | JP | disclosed |
| US-5728835-A | HYPOTENSIVE AGENTS; ANTIISCHEMIC AGENTS | TOA EIYO, LTD. (JP) | 1998-03-17 | — | — | US | disclosed |