Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.57 |
| ▸ | ACHE | P22303 | 2/20 | 0.53 |
| ▸ | PTGIR | P43119 | 3/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8710852 | 0.93 | HSD11B1 (0.51) | HTR2AACHESLC18A3HSD11B1 | |
| SCHEMBL8664405 | 0.87 | PTGIR (0.50) | HTR2AACHEPTGIRCHRM3KCNH2 | |
| SCHEMBL8715718 | 0.85 | HTR2A (0.61) | HTR2AACHEPTGIRCHRM3CHRM2 | |
| SCHEMBL8710974 | 0.84 | PTGIR (0.47) | HTR2AACHEPTGIRCHRM3MAPT | |
| Maleic Acid SCHEMBL8716551 | 0.83 | PTGIR (0.46) | HTR2AACHEPTGIRCHRM3KCNH2 | |
| Fumaric Acid SCHEMBL8716555 | 0.83 | PTGIR (0.46) | HTR2AACHEPTGIRCHRM3KCNH2 | |
| SCHEMBL9232680 | 0.81 | HSD11B1 (0.56) | HTR2AACHEHSD11B1MGLL | |
| Fumaric Acid SCHEMBL8711107 | 0.81 | PTGIR (0.44) | HTR2AACHEPTGIRCHRM3MAPT | |
| SCHEMBL8711207 | 0.81 | LMNA (0.49) | HTR2ASLC18A3 | |
| Fumaric Acid SCHEMBL8711104 | 0.81 | PTGIR (0.44) | HTR2AACHEPTGIRCHRM3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5728835-A | HYPOTENSIVE AGENTS; ANTIISCHEMIC AGENTS | TOA EIYO, LTD. (JP) | 1998-03-17 | — | — | US | disclosed |