SCHEMBL8664478

SCHEMBL8664478

CC[Si](CC)(CC)c1ccccc1S(=O)(=O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MYC P01106 1/20 0.41
POLB P06746 1/20 0.36
TSHR P16473 3/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
TTR P02766 2/20 0.35
HSD17B10 Q99714 2/20 0.34
LMNA P02545 1/20 0.34
HPGD P15428 1/20 0.34
HIF1A Q16665 1/20 0.34
CA12 O43570 2/20 0.33
CA9 Q16790 2/20 0.33
CYP1A2 P05177 1/20 0.33
PSIP1 O75475 1/20 0.33
RAPGEF4 Q8WZA2 1/20 0.33
FABP4 P15090 1/20 0.33
CCNA2 P20248 1/20 0.33
CDK2 P24941 1/20 0.33
MAPK14 Q16539 1/20 0.33
ALDH1A1 P00352 2/20 0.32
HTT P42858 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28492101 0.85 MYC (0.39) MYCPOLBTSHRSMN1; SMN2TTR
SCHEMBL28502898 0.82 CA12 (0.39) MYCTSHRCA12CA9ALDH1A1
SCHEMBL9633042 0.81 CA2 (0.45) CA12CA9CDK2
SCHEMBL2185772 0.78 MYC (0.44) MYCPOLBTSHRSMN1; SMN2TTR
SCHEMBL2687440 0.77 HSD17B10 (0.37) POLBTSHRSMN1; SMN2HSD17B10LMNA
SCHEMBL2778003 0.75 MYC (0.41) MYCPOLBTSHRSMN1; SMN2TTR
SCHEMBL8633298 0.75 TSHR (0.35) TSHRHSD17B10LMNAHPGDHIF1A
SCHEMBL2057737 0.75 TRPA1 (0.36) POLBTSHRSMN1; SMN2HSD17B10LMNA
SCHEMBL8661123 0.74 ALDH1A1 (0.35) POLBHSD17B10LMNAHPGDHIF1A
SCHEMBL7055834 0.73 TP53 (0.36) TSHRHPGDPSIP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112143028-B Application of substituted silicon-based benzene sulfonate in flame-retardant modification of high polymer material and flame-retardant high polymer material 中国科学院宁波材料技术与工程研究所 2021-07-27 CN disclosed
CN-112143028-A Application of substituted silicon-based benzene sulfonate in flame-retardant modification of high polymer material and flame-retardant high polymer material 中国科学院宁波材料技术与工程研究所 2020-12-29 CN disclosed
US-5847218-A Sulfonium salts and chemically amplified positive resist compositions SHIN-ETSU CHEMICAL CO., LTD. (JP) 1998-12-08 US disclosed