Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8663602 | 0.82 | AR (0.48) | ARPIK3CDPIK3R2PIK3CAPIK3CB | |
| SCHEMBL8664832 | 0.79 | HTR2A (0.43) | ARLMNAHSD17B10NPC1RAB9A | |
| SCHEMBL8662677 | 0.78 | PIK3CA (0.47) | LMNAHSD17B10NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8664432 | 0.74 | LMNA (0.47) | ARLMNAHSD17B10KDM4EALDH1A1 | |
| SCHEMBL8663503 | 0.71 | LMNA (0.49) | ARLMNAHSD17B10NPC1RAB9A | |
| SCHEMBL15362290 | 0.69 | HTR7 (0.62) | ARLMNAHSD17B10NPC1RAB9A | |
| SCHEMBL10772028 | 0.69 | LMNA (0.52) | ARLMNAHSD17B10NPC1RAB9A | |
| SCHEMBL8997879 | 0.69 | MAPT (0.43) | ARLMNAHSD17B10NPC1RAB9A | |
| SCHEMBL5133066 | 0.66 | LMNA (0.72) | ARLMNAHSD17B10NPC1RAB9A | |
| SCHEMBL254812 | 0.65 | LMNA (0.95) | ARLMNAHSD17B10NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852006-A | N-aminoalkyl-substituted nitrogen-containing six membered heterocyclic compounds | NIPPON CHEMIPHAR CO., LTD. (JP) | 1998-12-22 | — | — | US | disclosed |
| US-5574030-A | INHIBITING URINARY CONTRACTION, HETEROCYCLIC DIAMINES | NIPPON CHEMIPHAR CO., LTD. (JP) | 1996-11-12 | — | — | US | disclosed |