Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.57 |
| ▸ | HTR2A | P28223 | 1/20 | 0.57 |
| ▸ | ACHE | P22303 | 2/20 | 0.56 |
| ▸ | HTR6 | P50406 | 1/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8469854 | 0.97 | ACHE (0.57) | DRD2HTR2AACHESLC6A4 | |
| SCHEMBL1545276 | 0.94 | ACHE (0.59) | DRD2HTR2AACHESLC6A4 | |
| SCHEMBL7744954 | 0.84 | DRD2 (0.52) | DRD2HTR2AACHESLC6A4 | |
| SCHEMBL1545853 | 0.83 | ACHE (0.60) | DRD2HTR2AACHEHTR6SLC6A4 | |
| Hydrochloric Acid SCHEMBL8627510 | 0.82 | ACHE (0.56) | DRD2HTR2AACHESLC6A4 | |
| SCHEMBL791048 | 0.80 | DRD2 (0.70) | DRD2HTR2AACHEHTR6SLC6A4 | |
| SCHEMBL8788161 | 0.79 | DRD2 (0.40) | DRD2HTR2AACHEHTR6SLC6A4 | |
| SCHEMBL21848653 | 0.79 | DRD2 (0.53) | DRD2HTR2AHTR6 | |
| Hydrochloric Acid SCHEMBL9596033 | 0.79 | DRD2 (0.69) | DRD2HTR2AACHEHTR6SLC6A4 | |
| SCHEMBL21848641 | 0.79 | DRD2 (0.53) | DRD2HTR2AHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811435-A | 2- (4-heteroaryl-1-piperidinyl)alkyl!-1,3-dioxanes and related compounds and their therapeutic utility | HOECHST MARION RUSSEL, INC. | 1998-09-22 | — | — | US | disclosed |