Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | APLNR | P35414 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CCR1 | P32246 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
| ▸ | CCR8 | P51685 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12457564 | 0.86 | APLNR (0.37) | APLNRTSHRALDH1A1CCR1CCR5 | |
| SCHEMBL18648926 | 0.80 | CCR1 (0.39) | APLNRCCR1CCR5CCR8HDAC6 | |
| SCHEMBL19185580 | 0.79 | NOS2 (0.38) | MAPTTSHRALDH1A1PKMKDM4E | |
| SCHEMBL22223284 | 0.77 | CYP11B1 (0.37) | KDM4E | |
| SCHEMBL1332985 | 0.77 | CCR1 (0.31) | APLNRCCR1CCR5CCR8HDAC6 | |
| SCHEMBL22223412 | 0.77 | HRH1 (0.42) | APLNRCCR1CCR5CCR8HDAC6 | |
| SCHEMBL12527781 | 0.77 | L3MBTL1 (0.38) | MAPTALDH1A1KDM4EADRA2AADRA2B | |
| SCHEMBL19185634 | 0.76 | KCNH2 (0.41) | MAPTALDH1A1KDM4EADRA2AADRA2B | |
| SCHEMBL19185731 | 0.76 | KCNH2 (0.41) | MAPTALDH1A1KDM4EADRA2AADRA2B | |
| SCHEMBL20041788 | 0.76 | KCNH2 (0.41) | MAPTALDH1A1KDM4EADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763461-A | ANTIPICORNAVIRAL AGENTS | SANOFI (FR) | 1998-06-09 | — | — | US | disclosed |
| US-5618821-A | VIRICIDES, PICORNAVIRUS | SANOFI, S.A. (FR) | 1997-04-08 | — | — | US | disclosed |
| WO-1995031438-A1 | THERAPEUTIC PHENOXYALKYLHETEROCYCLES | SANOFI WINTHROP, INC. (US) | 1995-11-23 | — | — | WO | disclosed |