Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.35 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL108995 | 0.79 | — | — | |
| SCHEMBL1065203 | 0.79 | TSHR (0.54) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL1944726 | 0.78 | TSHR (0.50) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL399092 | 0.76 | TSHR (0.50) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL6535870 | 0.73 | ZDHHC20 (0.47) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL6209915 | 0.73 | — | — | |
| SCHEMBL28049835 | 0.72 | KDM4E (0.38) | TSHRALDH1A1KDM4E | |
| SCHEMBL2437345 | 0.72 | TSHR (0.56) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL13879266 | 0.72 | ZDHHC20 (0.50) | TSHRMAPK1ZDHHC20ZDHHC2 | |
| SCHEMBL20613909 | 0.72 | TSHR (0.41) | TSHRALDH1A1MAPK1TDP1ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726267-A | POLYETHER-ACRYLIC AMIDE COPOLYMERS, BINDERS FOR CERAMICS, LOW VISCOSITY | NALCO CHEMICAL COMPANY (US) | 1998-03-10 | — | — | US | disclosed |