Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 9/20 | 0.39 |
| ▸ | RARG | P13631 | 8/20 | 0.39 |
| ▸ | CYP26A1 | O43174 | 6/20 | 0.39 |
| ▸ | RARA | P10276 | 6/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.39 |
| ▸ | CRABP2 | P29373 | 1/20 | 0.39 |
| ▸ | CYP26B1 | Q9NR63 | 2/20 | 0.32 |
| ▸ | RXRA | P19793 | 2/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
| ▸ | RXRG | P48443 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3838094 | 0.74 | RARB (0.57) | RARBRARGCYP26A1RARACYP3A4 | |
| SCHEMBL768819 | 0.63 | MAP3K14 (0.40) | CYP3A4TP53TSHRALDH1A1 | |
| SCHEMBL14969273 | 0.63 | TP53 (0.33) | TP53TSHR | |
| SCHEMBL9531758 | 0.62 | TSHR (0.40) | CYP3A4TP53TSHRALDH1A1 | |
| SCHEMBL8522445 | 0.60 | RARB (0.59) | RARBRARGCYP26A1RARACYP3A4 | |
| SCHEMBL8457553 | 0.60 | RARB (0.65) | RARBRARGCYP26A1RARACYP3A4 | |
| SCHEMBL768915 | 0.60 | TSHR (0.40) | CYP3A4TP53TSHRALDH1A1 | |
| SCHEMBL779741 | 0.60 | ADRA1A (0.39) | CYP3A4TP53TSHRALDH1A1 | |
| SCHEMBL1494683 | 0.59 | — | — | |
| SCHEMBL8361240 | 0.59 | RARB (0.57) | RARBRARGCYP26A1RARACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849923-A | Heterocyclic-substituted naphthalenyl retinobenzoic acid derivatives | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-12-15 | — | — | US | disclosed |